Protein Alignment mbt and Stk4

DIOPT Version :10

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_067395.1
• Gene: Stk4 / 58231
• MGIID: 1929004
• Length: 487
• Species: Mus musculus
• Alignment Length: 274
• Identity: 110/274 - (40%)
• Similarity: 166/274 - (60%)
• Gaps: 4/274 - (1%)

  Fly   364 PRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVET 428
            |.|..|...|:||||.|:|..|..|.||:.||:|::.:....:.  :..|:.||:....|::|:.
Mouse    26 PEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE--IIKEISIMQQCDSPHVVKY 88

  Fly   429 YSSFLVNDELWVVMEYLEGGALTDIV--THSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSD 491
            |.|:..|.:||:||||...|:::||:  .:..:.|::|||:.:..||.|.|||....||||||:.
Mouse    89 YGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153

  Fly   492 SILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556
            :|||..:|..||:|||...|::..:.||.:::|||:||:||||..:.|....|||||||..|||.
Mouse   154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMA 218

  Fly   557 DGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQ 621
            :|:||:.:..|::|:..|....||..:.....|.....|:.:.||:.|.|||||.:||.|||::.
Mouse   219 EGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPFVKS 283

  Fly   622 AGPPSLLVPLMRNA 635
            |...|:|..|:..|
Mouse   284 AKGVSILRDLINEA 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	105/257 (41%)
Stk4	NP_067395.1	STKc_MST1_2	26..281	CDD:132943	104/256 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..334
		SARAH_MST1	432..480	CDD:439181