DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and taok2a

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_009297645.1	Gene:	taok2a / 556172	ZFINID:	ZDB-GENE-030131-9416	Length:	1141	Species:	Danio rerio

Alignment Length:	281	Identity:	105/281 - (37%)
Similarity:	150/281 - (53%)	Gaps:	12/281 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 DPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRREL---LFNEVVIMRDYHHPN 424
            ||.:......:||.||.|.|..|.|..:...||:|||....:|..|.   :..||..::...|||
Zfish    23 DPEKLFTDLREIGHGSFGAVYFAHDVRSNEVVAIKKMSFSGKQSNEKWQDIIKEVKFLQKLRHPN 87

  Fly   425 IVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR-MDEEQIATVCKQCLKALAYLHSQGVIHRDI 488
            .:|....:|.....|:||||..|.|...:..|.: :.|.:||.:....|:.||||||..:||||:
Zfish    88 TIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAITHGALQGLAYLHSHNMIHRDV 152

  Fly   489 KSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRL---PYGPEVDIWSLGI 550
            |:.:|||...|:|||.|||..:.||    ...|.|||||||:||||..:   .|..:||:|||||
Zfish   153 KAGNILLTEPGQVKLGDFGSASIVS----PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGI 213

  Fly   551 MVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLA 615
            ..||:.:.:||.||...:.|:..|...:.|.|.:.| .|...::|:|..|.:.|..|.|:..||.
Zfish   214 TSIELAERKPPLFNMNAMSALYHIAQNESPVLASNH-WSDYFRNFVDSCLQKIPQDRPTSDVLLN 277

  Fly   616 HPFLRQAGPPSLLVPLMRNAR 636
            |.||.:..|.|:::.|:...:
Zfish   278 HHFLCRERPHSVVMDLITRTK 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	101/263 (38%)
		S_TKc	372..619	CDD:214567	98/253 (39%)
taok2a	XP_009297645.1	PKc_like	6..318	CDD:304357	105/281 (37%)
taok2a	XP_009297645.1	S_TKc	28..281	CDD:214567	98/257 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910