| Sequence 1: | NP_523375.2 | Gene: | mbt / 32631 | FlyBaseID: | FBgn0025743 | Length: | 639 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001122092.1 | Gene: | PAK1 / 5058 | HGNCID: | 8590 | Length: | 553 | Species: | Homo sapiens |
| Alignment Length: | 611 | Identity: | 207/611 - (33%) |
|---|---|---|---|
| Similarity: | 294/611 - (48%) | Gaps: | 162/611 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 KKKKKPLISMPSNFEHRVHTGFDKRENKYVGLPLQWASIVGNNQILKSSNRPLPLVDPSEITPTE 68
Fly 69 ILDLKTIVRPHHNNNKADTTSLNSSSTMMMGSMAPMNPMAPGAHPMMSHGPGMMMPPETGGIVLP 133
Fly 134 KTSHVARSNSLRSSSPPRVRRVANVPPSVPEEEGPPAAGTPGVGGASSGGFKPPGAHPSLLYNSQ 198
Fly 199 HAHANGATGPLAVRTDQTNLQQYRSNLAPPSGGSMPQQQQTSPVGSVASGTRSNHSHTNNGNSGG 263
Fly 264 SYPPMYPTSHQQQQQQQQQAKQGGDQNQNPLHPHAHPHPHHHQHLAKSASRASSSSGGASSAAQQ 328
Fly 329 ASGASGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQ 393
Fly 394 VAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR 458
Fly 459 MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLV 523
Fly 524 GTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKV 588
Fly 589 SPRLQSFLDRMLVRDPAQRATAAELL 614 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| mbt | NP_523375.2 | CRIB_PAK_like | 9..54 | CDD:238526 | 20/44 (45%) |
| STKc_PAK_II | 360..620 | CDD:270815 | 145/255 (57%) | ||
| S_TKc | 372..619 | CDD:214567 | 140/243 (58%) | ||
| PAK1 | NP_001122092.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..77 | 4/8 (50%) | |
| Autoregulatory region | 70..140 | 25/78 (32%) | |||
| PBD | 74..128 | CDD:334253 | 22/62 (35%) | ||
| GTPase-binding | 75..105 | 15/29 (52%) | |||
| Interaction with CRIPAK. /evidence=ECO:0000269|PubMed:16278681 | 132..270 | 41/290 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 159..198 | 13/112 (12%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 211..251 | 12/109 (11%) | |||
| STKc_PAK_I | 262..517 | CDD:270814 | 145/255 (57%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0578 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D757766at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||