DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and msn

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_524679.3	Gene:	msn / 44030	FlyBaseID:	FBgn0010909	Length:	1504	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	101/273 - (36%)
Similarity:	157/273 - (57%)	Gaps:	17/273 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 DPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDY-HHPNIV 426
            ||....:....:|.|:.|.|.......||:..|:|.||:.:.:..|:.. |:.:::.| :|.||.
  Fly    27 DPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTEDEEEEIKL-EINVLKKYSNHRNIA 90

  Fly   427 ETYSSFL------VNDELWVVMEYLEGGALTDIVTHSR---MDEEQIATVCKQCLKALAYLHSQG 482
            ..|.:|:      .:|:||:||||...|::||:|..::   :.||.||.:|::.|:.|:||||..
  Fly    91 TYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLKEEWIAYICREILRGLSYLHSNK 155

  Fly   483 VIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVIS-----RLPYGPE 542
            |||||||..::||..:..|||.|||..||:.:.:.:|.:.:||||||:||||:     ...|...
  Fly   156 VIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGTPYWMAPEVIACDENPDATYDNR 220

  Fly   543 VDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQR 607
            .|:|||||..:||.:.:||..:..|::|:..|....||.|| :.|.|.:...|:|.:||:|..||
  Fly   221 SDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLK-SKKWSKKFHGFIDTVLVKDYHQR 284

  Fly   608 ATAAELLAHPFLR 620
            .....||.|.|::
  Fly   285 PYTENLLKHGFIK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	101/271 (37%)
		S_TKc	372..619	CDD:214567	98/261 (38%)
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	100/270 (37%)
		S_TKc	32..296	CDD:214567	98/265 (37%)
		CNH	1183..1484	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438568
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940