DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and GckIII

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_650596.1	Gene:	GckIII / 42064	FlyBaseID:	FBgn0266465	Length:	642	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	101/271 - (37%)
Similarity:	157/271 - (57%)	Gaps:	3/271 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 DPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRK-QQRRELLFNEVVIMRDYHHPNIV 426
            ||........:||:||.|.|....|..|.:.||:|.:||.: :...:.:..|::::.....|.:.
  Fly     8 DPELIFTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIDDIQQEIMVLSQCDSPYVT 72

  Fly   427 ETYSSFLVNDELWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSD 491
            :.|.|||...:||::||||.||:..|::.....:|..|..:.::.||.|.||||:..:|||||:.
  Fly    73 KYYGSFLKGTKLWIIMEYLGGGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSERKLHRDIKAA 137

  Fly   492 SILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556
            ::||:..|.|||:|||...|::....||.:.||||:||:||||.:..|..:.|||||||..||:.
  Fly   138 NVLLSEQGDVKLADFGVAGQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELA 202

  Fly   557 DGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQ 621
            .||||.....|::.:..|....||.|..::..|  .:.|::..|.:||..|.||.|||.:||:::
  Fly   203 KGEPPNSELHPMRVLFLIPKNNPPQLTGSYTKS--FKDFVEACLNKDPENRPTAKELLKYPFIKK 265

  Fly   622 AGPPSLLVPLM 632
            |...:.|:.|:
  Fly   266 AKKNAYLIDLI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	98/257 (38%)
		S_TKc	372..619	CDD:214567	95/247 (38%)
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	99/267 (37%)
GckIII	NP_650596.1	S_TKc	13..263	CDD:214567	95/251 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840