Protein Alignment mbt and Taok2

DIOPT Version :10

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001157247.1
• Gene: Taok2 / 381921
• MGIID: 1915919
• Length: 1240
• Species: Mus musculus
• Alignment Length: 311
• Identity: 109/311 - (35%)
• Similarity: 162/311 - (52%)
• Gaps: 22/311 - (7%)

  Fly   333 SGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVK 397
            :||.||..| |..:....|:         .||.:......:||.||.|.|..|.|......||:|
Mouse     3 AGGRAGSLK-DPDVAELFFK---------DDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIK 57

  Fly   398 KMDLRKQQRREL---LFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR- 458
            ||....:|..|.   :..||..::...|||.::....:|.....|:||||..|.|...:..|.:
Mouse    58 KMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKP 122

  Fly   459 MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLV 523
            :.|.:||.|....|:.||||||..:||||:|:.:|||:..|.|||.|||..:.::    ...|.|
Mouse   123 LQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMA----PANSFV 183

  Fly   524 GTPYWMSPEVISRL---PYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNA 585
            ||||||:||||..:   .|..:||:|||||..||:.:.:||.||...:.|:..|...:.|.|::.
Mouse   184 GTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSG 248

  Fly   586 HKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNAR 636
            | .|...::|:|..|.:.|..|.|:..||.|.|:.:..||::::.|::..:
Mouse   249 H-WSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	99/266 (37%)
Taok2	NP_001157247.1	STKc_TAO2	12..319	CDD:270804	104/301 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	320..463
		Smc	<474..>754	CDD:440809
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	899..946
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1212..1240