DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and hpo

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	104/275 - (37%)
Similarity:	159/275 - (57%)	Gaps:	12/275 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   364 PRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVK----KMDLRKQQRRELLFNEVVIMRDYHHPN 424
            |.:..|...|:||||.|:|..|..|.:...||:|    :.||.:      :..|:.||:....|.
  Fly    38 PEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHE------IIKEISIMQQCDSPY 96

  Fly   425 IVETYSSFLVNDELWVVMEYLEGGALTDI--VTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRD 487
            :|..|.|:....:||:.|||...|:::||  :....:.|::|||:....|:.|.|||.:..||||
  Fly    97 VVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRD 161

  Fly   488 IKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMV 552
            ||:.:|||..:|..||:|||...|::..:.||.:::|||:||:||||..:.|....|||||||..
  Fly   162 IKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITA 226

  Fly   553 IEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHP 617
            :||.:|:||:....|::|:..|....||:.:...:.|.....|:.:.||::|..||||.|||.|.
  Fly   227 LEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHE 291

  Fly   618 FLRQAGPPSLLVPLM 632
            |:|.|...|:|.|::
  Fly   292 FIRNAKHRSILKPML 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	99/261 (38%)
		S_TKc	372..619	CDD:214567	96/252 (38%)
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	98/260 (38%)
		S_TKc	42..293	CDD:214567	97/256 (38%)
		Mst1_SARAH	608..655	CDD:288481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438560
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940