DRSC/TRiP Functional Genomics Resources

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Protein Alignment mbt and hppy

DIOPT Version :10

Sequence 1:NP_523375.2 Gene:mbt / 32631 FlyBaseID:FBgn0025743 Length:639 Species:Drosophila melanogaster
Sequence 2:NP_725863.1 Gene:hppy / 37203 FlyBaseID:FBgn0263395 Length:1218 Species:Drosophila melanogaster


Alignment Length:269 Identity:109/269 - (40%)
Similarity:161/269 - (59%) Gaps:8/269 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   359 VSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHP 423
            :|..:|::..:...|||.|:.|.|..|....:....|:|.:.|......:::..|:::|||..||
  Fly    17 ISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHP 81

  Fly   424 NIVETYSSFLVNDELWVVMEYLEGGALTDI--VTHSRMDEEQIATVCKQCLKALAYLHSQGVIHR 486
            ||:..|.|:|..|:||:.||:..||:|.||  || ..:.|.|||.:|::.||.|.||||.|.:||
  Fly    82 NIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVT-GPLTEVQIAYMCRETLKGLEYLHSMGKMHR 145

  Fly   487 DIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVIS---RLPYGPEVDIWSL 548
            |||..:|||...|.|||:|||..||::..:.||||.:||||||:|||.:   :..|....|||:.
  Fly   146 DIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAC 210

  Fly   549 GIMVIEMVDGEPPFFNEPPLQAMRRI--RDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAA 611
            ||..||:.:.:||.|:..|::|:..:  ...:||.|.|..|.||...:|:...|.::|.:|.||.
  Fly   211 GITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAE 275

  Fly   612 ELLAHPFLR 620
            .||.|||::
  Fly   276 RLLQHPFVQ 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mbtNP_523375.2 CRIB_PAK_like 9..54 CDD:238526
STKc_PAK_II 360..620 CDD:270815 109/266 (41%)
hppyNP_725863.1 STKc_MAP4K3_like 25..283 CDD:270788 106/258 (41%)
CNH 864..1193 CDD:470577
Blue background indicates that the domain is not in the aligned region.

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