Protein Alignment mbt and max-2

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001300485.1
• Gene: max-2 / 3565400
• WormBaseID: WBGene00003144
• Length: 649
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 227/712 - (31%)
• Similarity: 322/712 - (45%)
• Gaps: 191/712 - (26%)

  Fly    11 ISMPSNFEHRVHTGFDKRENKYVGLPLQWASI--------------------------------- 42
            ||.|.|..||||.|:|.:  |:.|||..|..|
 Worm    41 ISQPYNTVHRVHVGYDGQ--KFSGLPQPWMDILLRDISYFSLADQKKDPNAVVTALKFYAQSMKE 103

  Fly    43 ------VGNNQILKSSN----------------RPLPLVDPSEITP-TEILDLKTIVRPHHN-NN 83
                  :..|.:..:|:                |.|...:.|..:| |.:....:..||..| ||
 Worm   104 NEKTKFMTTNSVFTNSDDDDVDVQLTGQVTEHLRNLQCSNGSATSPSTSVSASSSSARPLTNGNN 168

  Fly    84 KADT-----TSLNSSSTMMMGSMAPMNPMA-------------PGAHPMMSHGPGMMMPPETGGI 130
            ...|     |||:.|....:.|.||: |.:             |..||.....|   .||
 Worm   169 HLSTASSTDTSLSLSERNNVPSPAPV-PYSESAPQLKTFTGETPKLHPRSPFPP---QPP----- 224

  Fly   131 VLPKTSHVARSNSLRSSSPPRVRRVANVPPSVPEEEGPPAAGTPGVGGASSGGFKPPGAHPSLLY 195
            |||:.|..|.:.:..:::|....   ..||.||..:|||.               ||  .||.|.
 Worm   225 VLPQRSKTASAVATTTTNPTTSN---GAPPPVPGSKGPPV---------------PP--KPSHLK 269

  Fly   196 NSQHAHANGATGPLAVRTDQTNLQQYRSNLAPPSGGSMPQQQQTSPVGSVASGTRSNH----SHT 256
            .:....::|.:.|          |||.|  |...|.|:..       |||.|.|.|:.    |:.
 Worm   270 IASSTVSSGCSSP----------QQYSS--ARSVGNSLSN-------GSVVSTTSSDGDVQLSNK 315

  Fly   257 NNGNSGGSYPPMYPTSHQQQQQQQQQAKQGGDQNQN------PLHPHAHPHPHHHQHLAKSASRA 315
            .|.|.                      |..||:|.|      .:.|   |.|.......:::.|
 Worm   316 ENSND----------------------KSVGDKNGNTTTNKTTVEP---PPPEEPPVRVRASHR- 354

  Fly   316 SSSSGGASSAAQQASGASGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTG 380
                                        ::|:..:....|:.:|:..:|....:...:||.|::|
 Worm   355 ----------------------------EKLSDSEVLNQLREIVNPSNPLGKYEMKKQIGVGASG 391

  Fly   381 TVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVN-DELWVVMEY 444
            ||.:|....:...||||:|..:.|.::|:|..|:.:|:.|.|||:|....|:||: |:|||||:|
 Worm   392 TVFVANVAGSTDVVAVKRMAFKTQPKKEMLLTEIKVMKQYRHPNLVNYIESYLVDADDLWVVMDY 456

  Fly   445 LEGGALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFC 509
            ||||.|||:|..:.:||.|||.|.::|||||.:||...::|||||||::||..:|.|||:|.|||
 Worm   457 LEGGNLTDVVVKTELDEGQIAAVLQECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFC 521

  Fly   510 AQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRI 574
            ||: |...||.::||||||||||::::..|..:|||||||||.:||:|||||:..|.||:|:..|
 Worm   522 AQI-QPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDGEPPYLRETPLKAIYLI 585

  Fly   575 RDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNAR 636
            .....|.:|...::|....:|||:.||.||.|||...||||||||::|.|.|.|:|.:|..|
 Worm   586 AQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPFLKKAKPLSSLIPYIRAVR 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526	18/97 (19%)
		STKc_PAK_II	360..620	CDD:270815	128/260 (49%)
		S_TKc	372..619	CDD:214567	126/247 (51%)
max-2	NP_001300485.1	STKc_PAK	378..631	CDD:270789	127/253 (50%)
		S_TKc	379..630	CDD:214567	126/251 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920