Protein Alignment mbt and Pak3

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_008771626.1
• Gene: Pak3 / 29433
• RGDID: 3251
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 222/644 - (34%)
• Similarity: 332/644 - (51%)
• Gaps: 145/644 - (22%)

  Fly     4 KKKKKPLISMPSNFEHRVHTGFDKRENKYVGLPLQWASIVGNNQILKSSNRPLPLVDPSEITPTE 68
            |:|::|.||:||:|||.:|.|||....::...|.|             ::||:
  Rat    63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQ-------------TSRPV------------ 102

  Fly    69 ILDLKTIVRPHHNNNKADTTSLNSSSTMMMGSMAPMNPMAPGAHPMMSHGPGMMMPPETGGIVLP 133
                 |:..........|          :.||.     |.||..|     .|:   ||....:|
  Rat   103 -----TVASSQSEGKLPD----------LYGSQ-----MCPGKLP-----EGI---PEQWARLL- 138

  Fly   134 KTSHVARSNSLRSSSPPRVRRVANVPPSVPEEEGPPAAGTPGVGGASSGGFKPPGAHPSLLYNSQ 198
            :||::.:..  :..:|..|..|..                                    .|:|:
  Rat   139 QTSNITKLE--QKKNPQAVLDVLK------------------------------------FYDSK 165

  Fly   199 HAHANGATGPLAVRTDQTNLQQYRSNLAPPSGGSMPQQQQTSPVGSVASGTRSNH----SHTNNG 259
                           :..|.|:|.                     |..||.:|.|    :|.:|.
  Rat   166 ---------------ETVNNQKYM---------------------SFTSGDKSAHGYIAAHQSNT 194

  Fly   260 NSGGSYPPMYPTSHQQQQQQQQQAKQGGDQNQNPLHPHAHPHPHHHQHL-AKSASRASSSSGGAS 323
            .: .|.||:.|...:::.:::::.:   |.|:.|  |...|.|.|.:.: .:|...:.:|....:
  Rat   195 KT-ASEPPLAPPVSEEEDEEEEEEE---DDNEPP--PVIAPRPEHTKSIYTRSVVESIASPAAPN 253

  Fly   324 SAAQQASGASGGAA------GQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTV 382
            ..|...|..:..::      .:.::..::|.|:....|:.:||.|||::....|.|||:|::|||
  Rat   254 KEATPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTV 318

  Fly   383 CIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEG 447
            ..|.|.:||::||:|:|:|::|.::||:.||:::||:..:||||....|:||.||||||||||.|
  Rat   319 YTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAG 383

  Fly   448 GALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQV 512
            |:|||:||.:.|||.|||.||::||:||.:|||..|||||||||:|||..||.|||:|||||||:
  Rat   384 GSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQI 448

  Fly   513 SQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDM 577
            :.|..||.::|||||||:|||::|..|||:|||||||||.||||:||||:.||.||:|:..|...
  Rat   449 TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATN 513

  Fly   578 QPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNAR 636
            ..|.|:|..::|...:.||:|.|..|..:|.:|.|||.||||:.|.|.|.|.||:..|:
  Rat   514 GTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAK 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526	14/44 (32%)
		STKc_PAK_II	360..620	CDD:270815	148/259 (57%)
		S_TKc	372..619	CDD:214567	142/246 (58%)
Pak3	XP_008771626.1	PBD	69..162	CDD:395634	32/184 (17%)
		STKc_PAK3	284..580	CDD:132987	159/289 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820