Protein Alignment mbt and pak2a

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001002717.1
• Gene: pak2a / 266749
• ZFINID: ZDB-GENE-021011-2
• Length: 517
• Species: Danio rerio
• Alignment Length: 633
• Identity: 211/633 - (33%)
• Similarity: 301/633 - (47%)
• Gaps: 190/633 - (30%)

  Fly     4 KKKKKPLISMPSNFEHRVHTGFDKRENKYVGLPLQWASIVGNNQILKSSNRPLPLVDPSEITPTE 68
            |.|::|.||.||:|||.:|.|||....::.|:|.|||.::..:.|.||..:.         .|..
Zfish    68 KDKERPEISNPSDFEHTIHVGFDSVTGEFTGMPEQWARLLQTSNITKSEQKK---------NPQA 123

  Fly    69 ILDLKTIVRPHHNNNKADTTSLNSSSTMMMGSMAPMNPMAPGAHPMMSHGPGMMMPPETGGIVLP 133
            :||:....         |:|. ||....:.                                ...
Zfish   124 VLDVLKFY---------DSTG-NSRQKYLS--------------------------------FTD 146

  Fly   134 KTSHVARSNSLRSSSPPRVRRVANVPPSVPEEEGPPAAGTPGVGGASSGGFKPPGAHPSLLYNSQ 198
            |.:..|:..|  ..||.:       .|...:|:.||....|          :|           |
Zfish   147 KDAPQAKKGS--EQSPVK-------DPDDDDEDAPPPVVAP----------RP-----------Q 181

  Fly   199 HAHANGATGPLAVRTDQTNLQQYRSNLAPPSGGSMPQQQQTSPVGSVASGTRSNHSHTNNGNSGG 263
            |.        ::|.|        ||.:.|     :|
Zfish   182 HT--------ISVYT--------RSVIDP-----IP----------------------------- 196

  Fly   264 SYPPMYPTSHQQQQQQQQQAKQGGDQNQNPLHPHAHPHPHHHQHLAKSASRASSSSGGASSAAQQ 328
                                                            |..|.:.:.|:.:|.:|
Zfish   197 ------------------------------------------------APAAIADTDGSKAADKQ 213

  Fly   329 ASGASGGAAGQPKQDQRLTHEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQ 393
            ..|..           ::|.|:....|:.:||.|||::....:.|||:|::|||..|.|.:||::
Zfish   214 KKGKG-----------KMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVYTAIDVATGQE 267

  Fly   394 VAVKKMDLRKQQRRELLFNEVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSR 458
            ||:|:::|:||.::||:.||:::|::..:||||....||||.|||:||||||.||:|||:||.:.
Zfish   268 VAIKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSFLVGDELFVVMEYLAGGSLTDVVTETC 332

  Fly   459 MDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLV 523
            |||.|||.||::||:||.:||:..|||||||||::||..||.|||:|||||||::.|..||.::|
Zfish   333 MDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMV 397

  Fly   524 GTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKV 588
            ||||||:|||::|..|||:|||||||||.||||:||||:.||.||:|:..|.....|.|:|..|:
Zfish   398 GTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKL 462

  Fly   589 SPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQAGPPSLLVPLMRNAR 636
            ||..:.||:|.|..|..:|....|||.||||:.|.|.|.|.||:..|:
Zfish   463 SPIFRDFLNRCLEMDVEKRGGGKELLQHPFLKLAKPLSSLTPLILAAK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526	20/44 (45%)
		STKc_PAK_II	360..620	CDD:270815	145/259 (56%)
		S_TKc	372..619	CDD:214567	140/246 (57%)
pak2a	NP_001002717.1	PBD	74..129	CDD:279166	22/63 (35%)
		STKc_PAK2	222..517	CDD:132986	156/289 (54%)
		S_TKc	242..493	CDD:214567	140/250 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0578
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820