DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and cdc7

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_596340.1	Gene:	cdc7 / 2540660	PomBaseID:	SPBC21.06c	Length:	1062	Species:	Schizosaccharomyces pombe

Alignment Length:	250	Identity:	96/250 - (38%)
Similarity:	148/250 - (59%)	Gaps:	9/250 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   374 IGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRREL--LFNEVVIMRDYHHPNIVETYSSFLVND 436
            :|:|:.|.|....:...|..|||||:.|.|..:.:|  :..|:.::::..|||||:...|:..||
pombe    15 LGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIKMEIDLLKNLDHPNIVKYRGSYQTND 79

  Fly   437 ELWVVMEYLEGGALTDIVTH-SRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGR 500
            .|.:::||.|.|:|..|..: .::.|..:|....|.|:.|.|||:|||||||||..:||...||.
pombe    80 SLCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGT 144

  Fly   501 VKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNE 565
            :||:|||...:::  ..:..|:||:||||:||||..:......||||:|..|||::||.||:::.
pombe   145 IKLADFGVATKIN--ALEDHSVVGSPYWMAPEVIELVGATTASDIWSVGCTVIELLDGNPPYYDL 207

  Fly   566 PPLQAM-RRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFL 619
            .|..|: |.::|..||...|   :|...:|||.:...:||..|....:||.||::
pombe   208 DPTSALFRMVKDEHPPLPSN---ISSAAKSFLMQCFQKDPNLRIKTRKLLKHPWV 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	96/249 (39%)
		S_TKc	372..619	CDD:214567	96/248 (39%)
cdc7	NP_596340.1	STKc_Cdc7_like	10..259	CDD:270797	96/248 (39%)
cdc7	NP_596340.1	S_TKc	10..259	CDD:214567	96/248 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910