DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and Stk24

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_017171477.1	Gene:	Stk24 / 223255	MGIID:	2385007	Length:	443	Species:	Mus musculus

Alignment Length:	272	Identity:	110/272 - (40%)
Similarity:	161/272 - (59%)	Gaps:	4/272 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   363 DPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRK-QQRRELLFNEVVIMRDYHHPNIV 426
            ||.|......|||:||.|.|....|..|.:.||:|.:||.: :...|.:..|:.::.....|.:.
Mouse    31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVT 95

  Fly   427 ETYSSFLVNDELWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSD 491
            :.|.|:|.:.:||::||||.||:..|::....:||.||||:.::.||.|.||||:..||||||:.
Mouse    96 KYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAA 160

  Fly   492 SILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMV 556
            ::||:..|.|||:|||...|::....||.:.||||:||:||||.:..|..:.|||||||..||:.
Mouse   161 NVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELA 225

  Fly   557 DGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPF-LR 620
            .||||.....|::.:..|....||.|:..:  |..|:.|::..|.::|:.|.||.|||.|.| :|
Mouse   226 KGEPPHSELHPMKVLFLIPKNNPPTLEGNY--SKPLKEFVEACLNKEPSFRPTAKELLKHKFIIR 288

  Fly   621 QAGPPSLLVPLM 632
            .|...|.|..|:
Mouse   289 NAKKTSYLTELI 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	105/258 (41%)
		S_TKc	372..619	CDD:214567	102/248 (41%)
Stk24	XP_017171477.1	STKc_MST3_like	34..307	CDD:270786	108/269 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910