DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mbt and Map4k3

DIOPT Version :9

Sequence 1:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_038967654.1	Gene:	Map4k3 / 170920	RGDID:	621280	Length:	946	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	111/281 - (39%)
Similarity:	172/281 - (61%)	Gaps:	8/281 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 VSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHP 423
            :|..:|:|:.:...:||.|:.|.|..|.:.:||...|:|.:.|...:...::..|:::|:|..|.
  Rat     7 LSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHA 71

  Fly   424 NIVETYSSFLVNDELWVVMEYLEGGALTDI--VTHSRMDEEQIATVCKQCLKALAYLHSQGVIHR 486
            |||..:.|:|..|:||:.||:..||:|.||  || ..:.|.|||.|.::.|:.|.||||:|.:||
  Rat    72 NIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVT-GPLSELQIAYVSRETLQGLYYLHSKGKMHR 135

  Fly   487 DIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVIS---RLPYGPEVDIWSL 548
            |||..:|||..:|.|||:|||..||::..:.||||.:||||||:|||.:   :..|....|:|::
  Rat   136 DIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAV 200

  Fly   549 GIMVIEMVDGEPPFFNEPPLQAMRRI--RDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAA 611
            ||..||:.:.:||.|:..|::|:..:  .:.|||.||:..|.|.....|:...|.::|.:|.||.
  Rat   201 GITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAE 265

  Fly   612 ELLAHPFLRQAGPPSLLVPLM 632
            :||.|||:.|....||.:.|:
  Rat   266 KLLQHPFVTQPLTRSLAIELL 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	107/266 (40%)
		S_TKc	372..619	CDD:214567	103/253 (41%)
Map4k3	XP_038967654.1	STKc_MAP4K3_like	15..273	CDD:270788	103/258 (40%)
Map4k3	XP_038967654.1	CNH	583..926	CDD:214481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910