Protein Alignment mbt and pak4

DIOPT Version :9

• Sequence 1: NP_523375.2
• Gene: mbt / 32631
• FlyBaseID: FBgn0025743
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_012823244.1
• Gene: pak4 / 100036644
• XenbaseID: XB-GENE-1013749
• Length: 665
• Species: Xenopus tropicalis
• Alignment Length: 744
• Identity: 332/744 - (44%)
• Similarity: 401/744 - (53%)
• Gaps: 204/744 - (27%)

  Fly     1 MFSKKKKKPLISMPSNFEHRVHTGFDKRENKYVGLPLQWASIVGNNQILKSSNRPLPLVDPSEIT 65
            ||.||||:..||.|.|||||||||||::|.|:.|||.||.|:     |.:|:.||.||||||.||
 Frog    16 MFGKKKKRIEISAPLNFEHRVHTGFDQQEQKFTGLPRQWQSL-----IEESAKRPKPLVDPSYIT 75

  Fly    66 PTEILDLKTIVRPHHNNNKADTTSLNSSSTMMMGSMAPMNPMAPGAHPMMSHGPGMMMPPETGGI 130
            ....:..|||||       ....||:.|...::.....|:
 Frog    76 TINHVPQKTIVR-------GSKMSLDGSLAWLLDEFDAMS------------------------- 108

  Fly   131 VLPKTSHVARSNSLRSSSPP-----------------RVRR------------------------ 154
                   :.||||||..|||                 |||:
 Frog   109 -------ICRSNSLRRESPPCHPREDRFHQENGMSEVRVRQQREDGQRGSERNRSEHSRRERQRE 166

  Fly   155 ---------------------VANVPPSVPEEEG------------------------------- 167
                                 ..:.|..:||:.|
 Frog   167 EHKAVPQQPRGQEPSNKHRPPPPDYPKDIPEKRGTRSHEKGDGRREYPVNDRGYSEPVERVVKRE 231

  Fly   168 ------PPAAGTPGVGGASSGGFKPPGAHPSLLYNSQHAHANGATGPLAVRTDQTN--LQQYRSN 224
                  |.::.|...|...|...|.|.:.||:    :...::...|  .|:..||.  ...|...
 Frog   232 KGEEKRPKSSYTSAEGSPQSPRDKRPLSGPSI----RTPGSSSTEG--VVKQTQTGRAFNTYPRA 290

  Fly   225 LAPPSGGS---MPQQQQTSPVGSVASGTRSNHSHTNNGNSGGSYPPMYPTSHQQQQQQQQQAKQG 286
            ...||.|:   :|....|.|:.|.::.::|:                     .:.||.|.:.|..
 Frog   291 ETDPSRGAPHQVPDSHSTVPLDSKSTVSKSS---------------------SRPQQGQVKPKLP 334

  Fly   287 GDQNQNPLHPHAH----PHPHHHQHLAKSASRASSSSGGASSAAQQASGASGGAAGQPKQDQRLT 347
            ...:...|.||:.    .||...||.|:..|                         ..::.||::
 Frog   335 DKPHPTQLVPHSSDPQLSHPVQTQHPAQPRS-------------------------PQREPQRVS 374

  Fly   348 HEQFRAALQMVVSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFN 412
            ||||||||||||..||||..||:|.||||||||.|||||.||:|:.|||||||||||||||||||
 Frog   375 HEQFRAALQMVVDPGDPRTYLDNFIKIGEGSTGIVCIATIKSSGKLVAVKKMDLRKQQRRELLFN 439

  Fly   413 EVVIMRDYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTHSRMDEEQIATVCKQCLKALAY 477
            ||||||||.|.|:||.|:|:||.|||||:||:||||||||||||:||:||||||||...||||:.
 Frog   440 EVVIMRDYQHENVVEMYNSYLVGDELWVIMEFLEGGALTDIVTHTRMNEEQIATVCVSVLKALSV 504

  Fly   478 LHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVISRLPYGPE 542
            ||:|||||||||||||||..|||||||||||||||::|:|:|||||||||||:||:|||||||||
 Frog   505 LHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVNKEVPRRKSLVGTPYWMAPELISRLPYGPE 569

  Fly   543 VDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQR 607
            |||||||||||||||||||:||||||:||:.|||..||.||||.||||.|:.||||:|||||:||
 Frog   570 VDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPKLKNAQKVSPLLKGFLDRLLVRDPSQR 634

  Fly   608 ATAAELLAHPFLRQAGPPSLLVPLMRNAR 636
            |:|.|||.||||.:|||||.:|||||..|
 Frog   635 ASANELLKHPFLGKAGPPSCIVPLMRQNR 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526	24/44 (55%)
		STKc_PAK_II	360..620	CDD:270815	207/259 (80%)
		S_TKc	372..619	CDD:214567	199/246 (81%)
pak4	XP_012823244.1	CRIB_PAK_like	24..70	CDD:238526	28/50 (56%)
		PKc_like	374..665	CDD:389743	231/290 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	420	1.000	Domainoid score	I636
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4300
Inparanoid	1	1.050	595	1.000	Inparanoid score	I959
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131221at33208
OrthoFinder	1	1.000	-	-		FOG0001853
OrthoInspector	1	1.000	-	-		otm48630
Panther	1	1.100	-	-	O	PTHR48015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3286
SonicParanoid	1	1.000	-	-		X1054
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100