DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9784 and INP51

DIOPT Version :9

Sequence 1:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_012264.3	Gene:	INP51 / 854815	SGDID:	S000001264	Length:	946	Species:	Saccharomyces cerevisiae

Alignment Length:	417	Identity:	124/417 - (29%)
Similarity:	183/417 - (43%)	Gaps:	71/417 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQVLGLFKE 97
            ::..|:|:..:.|.:       .::|....|...:.: .:.|:|.:||:||.......:|.   .
Yeast   529 IFAGTFNISGKIPKD-------DIKDWIFPKSMSKED-EMADLYVIGLEEVVELTPGHMLA---T 582

  Fly    98 DP-----WTHKAKELL----RNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGI 153
            ||     |..|...||    |...|:.:.:.|:.|:||.:|:.......::.||.:..:|||||:
Yeast   583 DPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGM 647

  Fly   154 WGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHDYVFWF 218
            ..|||||:|.|.........:|:||.|....:::|..|||.|.::..:  .:...|.|||.:.|.
Yeast   648 ASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRF--SKGLRIKDHDAIIWM 710

  Fly   219 GDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLPAFPPTFKFREG 283
            ||.|:|:..|:.... |::|..|  :.:|.::|||.|.....: :|....|....||||:||..|
Yeast   711 GDFNYRILMSNEDVR-RKIVSKE--YASLFEKDQLNQQMIAGE-SFPYFHEMAIDFPPTYKFDPG 771

  Fly   284 TSEYDLK---RRPAWTDRIMYAVQPLNRQPGMQLSIEQCSYKSHPLYTISDHKPVTSDFTIKLYP 345
            |..||..   |.|||||||:...:.|          ||..||.......|||:||        |.
Yeast   772 TKNYDTSEKMRIPAWTDRILSRGEVL----------EQLEYKCCEDILFSDHRPV--------YA 818

  Fly   346 NVRAPGVVFSPLSLWKIGDENTVEYHKQAEFDEGSNDWIGIFPSEYASLAD--YVAYEYVNQAES 408
            ..||...|........:|   |..|.|..|..||.:|     ..:.|.|:|  :|       .||
Yeast   819 IFRARVTVVDEQKKTTLG---TQIYEKIMERLEGLDD-----DEKIAVLSDDAFV-------IES 868

  Fly   409 PSSSDS----NHQPDPFETPSHHRRGR 431
            ...|||    .|.|.|...|   :|||
Yeast   869 FEGSDSIAGPTHSPTPIPEP---KRGR 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	96/319 (30%)
INP51	NP_012264.3	COG5329	1..501	CDD:227637
INP51	NP_012264.3	COG5411	498..946	CDD:227698	124/417 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810