DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9784 and inpp5j

DIOPT Version :9

Sequence 1:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_002934320.2	Gene:	inpp5j / 779554	XenbaseID:	XB-GENE-984978	Length:	787	Species:	Xenopus tropicalis

Alignment Length:	512	Identity:	164/512 - (32%)
Similarity:	249/512 - (48%)	Gaps:	93/512 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TPK-IPDSEPDGSKGKGKQQLET----YRVYVVTWNVGSRFPDNISLRHLLGLQDVTVDKDTKET 68
            ||: |..|.....|.:|...::.    :|:||:|||||...|.: .|..||.|.    .:|.|
Frog   176 TPECIRPSPAKADKSQGDSTVDVAGKDFRIYVITWNVGCAVPPS-DLTSLLCLN----ARDDK-- 233

  Fly    69 NAHLPDIYALGLQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQ 133
                .|::.:||||||:...:::......|.|:....::|..:.||.|.:.:|||.||.:|.:..
Frog   234 ----IDMFVIGLQEVNSMINKRLKDALFSDQWSEVFMDVLSPFSYVLVSSVRMQGCLLLVFSKYF 294

  Fly   134 HVEHLQDIEAEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILEN 198
            |:..|:||:.:.||||.||.|||||.||:|.:|:|..:.|:..||.||....|:|:::::.||:.
Frog   295 HLPFLRDIQTDCTRTGLGGYWGNKGGVSIRLSLFGHMVCFLNCHLPAHMENTDQRVDNFESILQL 359

  Fly   199 HHYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQH--EALIQRDQLYQVREKSQ 261
            ..:.......:.|||.||||||||||::             |...|  ::.||.::|..:.||.|
Frog   360 QQFQGPLANGVLDHDLVFWFGDLNFRIE-------------DLDLHFVKSAIQGNKLALLWEKDQ 411

  Fly   262 L--------AFQVLQERLPAFPPTFKFREGTSEYDL---KRRPAWTDRIMYAVQ-PLNRQPGMQ- 313
            |        ......|....||||:||..||:.||.   ||:|||||||::.:: |:.:.|..|
Frog   412 LNMAKIFEPVLNGFMEGSLTFPPTYKFDVGTNTYDTSSKKRKPAWTDRILWKMKCPITQSPAKQL 476

  Fly   314 ---------LSIEQCSYKSHPLYTISDHKPVTSDFTIKLYPNVRAPGVVFSPLSLWKIGDENTVE 369
                     ||:...||.||..||.||||||::.|:::....:.||.|.......|...|:..|.
Frog   477 GTISTRSKELSVTLLSYGSHMQYTESDHKPVSAIFSLQFASCLAAPLVQLLVRDEWLQPDDAHVI 541

  Fly   370 YHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQAESPSSSDSNHQPDPFETPSHHRRGRHHH 434
            |.....:.:.|.||||::...:....|||:|.:....|              ||    .||:|.|
Frog   542 YRWCPGYMKSSWDWIGLYRVGFRHHKDYVSYVWAKSDE--------------ET----ERGKHQH 588

  Fly   435 RNRQRQRRHQEANAQELVRLDFADDVELRHGEQYLLIYFRSTGVRGVTSLAGVSGVF 491
                           |:|   |::::..:...:|||.||.:    .:.:|.||:..|
Frog   589 ---------------EVV---FSEELLPKGTSEYLLGYFSN----NLGTLIGVTEPF 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	123/333 (37%)
inpp5j	XP_002934320.2	INPP5c_INPP5J-like	203..513	CDD:197328	123/333 (37%)
		SKICH	524..625	CDD:407623	33/140 (24%)
		Abhydrolase	652..>749	CDD:419691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H136409
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D336369at33208
OrthoFinder	1	1.000	-	-		FOG0001973
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010