DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9784 and synj1

DIOPT Version :9

Sequence 1:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_005155414.1	Gene:	synj1 / 337236	ZFINID:	ZDB-GENE-030131-9180	Length:	1612	Species:	Danio rerio

Alignment Length:	430	Identity:	115/430 - (26%)
Similarity:	190/430 - (44%)	Gaps:	84/430 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 RVYVVTWNV--GSRFPDNISLRHLLGLQDVTVDKDTK-------ETNAHLPDIYALGLQE----- 82
            ||.|.||||  |.:|.......|.  |.|..:|...|       :...:..||:|:|.:|
Zfish   539 RVCVGTWNVNGGKQFRSIAFRNHT--LNDWLLDAPKKAGHPEFQDVKNNPVDIFAIGFEEMVELN 601

  Fly    83 ----VNAQPQQQVLGLFKEDPWTHK-AKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIE 142
                |:|....|.|       |..: .|.:.|:..||.:.:||:.|:.|.:|:|.||...::|:.
Zfish   602 AGNIVSASTTNQKL-------WAAELQKNISRDQRYVLLASEQLVGVCLFVFIRPQHAPFIRDVA 659

  Fly   143 AEFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYR 207
            .:..:||.||..||||.|::|...:...:.||.:|..|....:.||.:||.:|.....:.:.|.
Zfish   660 VDTVKTGMGGATGNKGGVAIRMLFHTTSICFVCSHFAAGQSQVKERNDDYNEIARKLSFPMGRL- 723

  Fly   208 EIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAFQVLQERLP 272
             :|.||||||.||.|:|:  :..:.||:||:|.:: .:|||..|||.:.:...|:....::.:|.
Zfish   724 -LYSHDYVFWCGDFNYRI--NIPNEEVKELIRQQN-WDALIGGDQLVEQKNAGQVFRGFIEGKLD 784

  Fly   273 AFPPTFKFREGTSEYDLK---RRPAWTDRIMYAVQ------------------PLNRQPGMQLSI 316
             |.||:|:...:.:||..   |.||||||:::..:                  |:|.:.....|.
Zfish   785 -FAPTYKYDLFSEDYDTSEKCRTPAWTDRVLWKRRKWNFDKTAEELELNVVGAPVNEEEQYPWSP 848

  Fly   317 EQCSYKSHPLYTISDHKPVTSDFTI-----------KLYPNVRA-----PGVVFSPLSLWKIGDE 365
            ....|........|||:||.:...:           ::|..|.|     .|.:.  :||...|.:
Zfish   849 GDLKYYGRAELKTSDHRPVVAIIDVDILEVDPEARHQVYKEVIALQGPPDGTIL--VSLCSSGPD 911

  Fly   366 NTVEYHKQAEFDEGSNDWIGIFPSEYASLADYVAYEYVNQ 405
               :|...|..|:        ...::|:..:.:...:|.:
Zfish   912 ---DYFDDALIDD--------LLDKFANFGEVILIRFVEE 940

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	103/348 (30%)
synj1	XP_005155414.1	Syja_N	60..340	CDD:280532
		INPP5c_Synj1	538..873	CDD:197332	103/348 (30%)
		RRM_SF	872..1010	CDD:302621	12/82 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579649
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840