DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9784 and inppl1a

DIOPT Version :9

Sequence 1:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001034893.1	Gene:	inppl1a / 325179	ZFINID:	ZDB-GENE-030131-3904	Length:	1266	Species:	Danio rerio

Alignment Length:	344	Identity:	83/344 - (24%)
Similarity:	153/344 - (44%)	Gaps:	51/344 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SKGKGKQQLETYRVYVVTWNVGSRFPDNISLRHLLG--LQDVTVDKDTKETNAHLP-DIYALGLQ 81
            :|...:.:.:...:::.|||:||     :.....||  :....:.|...|....:| |||..|.|
Zfish   397 NKHSNQDEPDMISIFIGTWNMGS-----VPAPKPLGSWILSRGLGKTLDEMAVTIPHDIYVFGTQ 456

  Fly    82 EVNAQPQQQVLGLFKEDPWTHKAKELLRNY---DYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEA 143
            |.:...::          |....:..|:.|   :|..:..:.:..:.:.:.|:.:|...:..:..
Zfish   457 ENSVCDKE----------WVETLRCSLKEYTDMEYKPIAVQTLWNIKIVVLVKAEHENRISHVGM 511

  Fly   144 EFTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYRE 208
            ...:||.....||||||.|.|...|....||..|||:.:..:..|.::|..||.......|:...
Zfish   512 SSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKIHRRNQNYLDILRQLSLGDKQLNS 576

  Fly   209 IYD----HDYVFWFGDLNFRLQGSDSSTEVRELVR--DESQHEALIQRDQLYQVREKSQLAFQVL 267
             :|    ..::|||||||:||     ..:::|::.  :..:.:.|::.|||...|||:::..:..
Zfish   577 -FDISLRFTHLFWFGDLNYRL-----DMDIQEILNYINRKEFDPLLKVDQLNLEREKNKIFLRFA 635

  Fly   268 QERLPAFPPTFKFREGTSE-YDLKRR---------PAWTDRIMYAVQPLNRQPGMQLSIEQCSYK 322
            :|.: ::|||:::..|:.: |..:::         |:|.|||::...|       :..|...||.
Zfish   636 EEEI-SYPPTYRYERGSRDTYVWQKQKATGMRTNVPSWCDRILWKSYP-------ETHIVCNSYG 692

  Fly   323 SHPLYTISDHKPVTSDFTI 341
            .......|||.||...|.:
Zfish   693 CTDDIVTSDHSPVFGTFEV 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	82/331 (25%)
inppl1a	NP_001034893.1	SH2_SHIP	15..113	CDD:198206
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..159
		INPP5c_SHIP2-INPPL1	408..711	CDD:197335	82/331 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	879..951
		NPXY motif	958..961
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	986..1132
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1147..1174
		SAM_Ship2	1204..1263	CDD:188890
		SAM	1207..1263	CDD:197735
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910