DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9784 and Inppl1

DIOPT Version :9

Sequence 1:NP_001259623.1 Gene:CG9784 / 32629 FlyBaseID:FBgn0030761 Length:519 Species:Drosophila melanogaster
Sequence 2:NP_001116211.1 Gene:Inppl1 / 16332 MGIID:1333787 Length:1257 Species:Mus musculus


Alignment Length:439 Identity:114/439 - (25%)
Similarity:178/439 - (40%) Gaps:116/439 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 VYVVTWNVGS-RFPDNIS---LRHLLG--LQDVTVDKDTKETNAHLPDIYALGLQEVNAQPQQQV 91
            |::.|||:|| ..|.|::   ....||  |.:|||      |..|  |||..|.|| |:...::.
Mouse   427 VFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTV------TIPH--DIYVFGTQE-NSVGDREW 482

  Fly    92 LGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAEFTRTGFGGIWGN 156
            |.|.:..     .|| |.:.||..:..:.:..:.:::.|:.:|...:..:.....:||.....||
Mouse   483 LDLLRGG-----LKE-LTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGN 541

  Fly   157 KGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDYKQILENHHYHVKRYREIYDHD-------- 213
            ||||.|.|...|....||..|||:.:.....|.::|..||        |...:.|..        
Mouse   542 KGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDIL--------RLLSLGDRQLSAFDISL 598

  Fly   214 ---YVFWFGDLNFRLQGSDSSTEVRELVR--DESQHEALIQRDQLYQVREKSQLAFQVLQERLPA 273
               ::|||||||:||     ..:::|::.  ...:.|.|::.|||...|||.::..:..:|.: :
Mouse   599 RFTHLFWFGDLNYRL-----DMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEI-S 657

  Fly   274 FPPTFKFREGTSE-YDLKRR---------PAWTDRIMYAVQPLNRQPGMQLSIEQCSYKSHPLYT 328
            ||||:::..|:.: |...::         |:|.|||::...|       :..|...||.......
Mouse   658 FPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYP-------ETHIICNSYGCTDDIV 715

  Fly   329 ISDHKPVTSDFTIKLYPNVRAPGVV---FSPLSLWKIGDENTV---------------------- 368
            .|||.||...|.:         ||.   .|...|.|..|:..:                      
Mouse   716 TSDHSPVFGTFEV---------GVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFY 771

  Fly   369 -----EYHKQAEFDEGSNDWIGIFPSEYAS---------LADYVAYEYV 403
                 ||.|..|.|..|:|.|.....:::|         |||   .||:
Mouse   772 STCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILAD---IEYL 817

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9784NP_001259623.1 INPP5c_INPP5J-like 31..341 CDD:197328 94/336 (28%)
Inppl1NP_001116211.1 SH2_SHIP 17..119 CDD:198206
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..181
INPP5c_SHIP2-INPPL1 425..728 CDD:197335 94/336 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 897..986
SH3-binding 945..950
NPXY motif 984..987
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 999..1119
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1134..1196
SAM_Ship2 1193..1255 CDD:188890
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5411
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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