DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9784 and Inpp5e

DIOPT Version :9

Sequence 1:	NP_001259623.1	Gene:	CG9784 / 32629	FlyBaseID:	FBgn0030761	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_446084.1	Gene:	Inpp5e / 114089	RGDID:	620478	Length:	648	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	100/367 - (27%)
Similarity:	155/367 - (42%)	Gaps:	65/367 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GKQQLETY------RVYVVTWNVGSRFPDNISLRHLLGLQDV--TVDKDTKETNA-HLPDIYALG 79
            |..:|..|      .::|.|||             :.|.:::  ::|:....|.| :..|:|.:|
  Rat   290 GADELARYFPDRNMALFVATWN-------------MQGQKELPASLDEFLLPTEADYTQDLYVIG 341

  Fly    80 LQEVNAQPQQQVLGLFKEDPWTHKAKELLRNYDYVAVKTEQMQGLLLSMFVRRQHVEHLQDIEAE 144
            :||          |......|..:.:|.| ...||.:.:.....|.:|:|:||..:....::|..
  Rat   342 VQE----------GCSDRREWETRLQETL-GPQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYS 395

  Fly   145 FTRTGFGGIWGNKGAVSVRFTLYGCGLAFVVAHLTAHDHMMDERIEDY----------KQILENH 199
            ...|........|||:.|.||.:|....|:.:|.|:.|..:.||:.||          :.:.:.:
  Rat   396 TVTTRIVSQIKTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYNRTIQALALPRNVPDTN 460

  Fly   200 HYHVKRYREIYDHDYVFWFGDLNFRLQGSDSSTEVRELVRDESQHEALIQRDQLYQVREKSQLAF 264
            .|...........|.||||||.||||.|...:.|.......|....||:|.|||.:..:|..: |
  Rat   461 PYRSSAGDVTTRFDEVFWFGDFNFRLSGGRVAVEAFLKQDPEVDVLALLQHDQLTREMKKGSI-F 524

  Fly   265 QVLQERLPAFPPTFKFREGTSEYD---LKRRPAWTDRIMYAVQPLNRQPGMQLSIEQCSYKSHPL 326
            :..:|....|.|::||..|...||   .:|.|::|||::|.    :|..|   .|....|.|.|.
  Rat   525 KGFEEAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYK----SRHKG---DICPMKYSSCPG 582

  Fly   327 YTISDHKPVTSDFTIKLYP---NVRAPGVVFSPLSLWKIGDE 365
            ...|||:||...|.:|:.|   |:        ||:..|...|
  Rat   583 IKTSDHRPVYGLFRVKVRPGRDNI--------PLAAGKFDRE 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9784	NP_001259623.1	INPP5c_INPP5J-like	31..341	CDD:197328	91/331 (27%)
Inpp5e	NP_446084.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64
		4 X 4 AA repeats of P-X-X-P	59..243
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	99..158
		INPP5c_INPP5E-like	299..597	CDD:197329	90/329 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910