| Sequence 1: | NP_523374.2 | Gene: | SMC3 / 32627 | FlyBaseID: | FBgn0015615 | Length: | 1200 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005436.1 | Gene: | SMC3 / 9126 | HGNCID: | 2468 | Length: | 1217 | Species: | Homo sapiens |
| Alignment Length: | 1220 | Identity: | 653/1220 - (53%) |
|---|---|---|---|
| Similarity: | 893/1220 - (73%) | Gaps: | 25/1220 - (2%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MHIKQIIIQGFKSYKDQTVVEPFDKRHNVVVGRNGSGKSNFFYAIQFVLSDEFTHLRPEQRQSLL 65
Fly 66 HEGTGARVISAYVEIIFDNSDNRVPIDKEEIFLRRVIGAKKDQYFLNKKVVPRNEVVNLLESAGF 130
Fly 131 SSSNPYYIVKQGKINQMATAADSYRLKLLREVAGTRVYDERKEESLNLLRETDSKVEKISEYLKT 195
Fly 196 IEDRLQTLEEEKEELKEYQKWDKTRRTLEYIRYETELKDTKKALDELQLQRKSSSDKKKIYNIEI 260
Fly 261 QKAQEKIKDVQKNLKEAKKKVQSTKEERSVLMTEQQQLLREKTKLDLTIVDLNDEVQGDNKSKER 325
Fly 326 ADQELKNLKVTIAEREKELDDVKPKYEAMKRKEEDCSRELQLKEQKRKELYAKQGRGSQFSSRED 390
Fly 391 RDKWITNELKSISKQTRDKIAHHAKLVEDLK-KDATSEKDLGQ--KIEEHSSELEQLRLQIDEHN 452
Fly 453 KKYYELKKTKDQHQSMRNELWRKETQMTQQLQTHKEELSRADQALRSMAGKPILNGCDSVRKVLD 517
Fly 518 SFVERGGQSAEIARAYYGPVIENFSCDKTIYTAVEVTAANRLFHHIVESEYEGTQILKEMNKLKL 582
Fly 583 PGEVTFMPLNRLQVKIHDYPDDPDSIPMISKLKYDEQHDKALRYIFGKTLICRNLERATELAKST 647
Fly 648 GLDCVTLDGDQVSSKGSLTGGYFNTSRSRLEMQKKRTEYTSQIAEFEKKLSK-LRNELKSTENNI 711
Fly 712 NSIVSEMQKTETKQGKSKDVFEKVQGEIRLMKEELVRIEQYRAPKERSLAQCKASLESMTSTKSS 776
Fly 777 LEAELKQELMSTLSSQDQREIDQLNDDIRRLNQENKEAFTQRMQFEVRKNKLDNLLINNLFRRRD 841
Fly 842 ELIQALQEISVEDRKRKLNNCKTELVSAEKRIKKVNSDLEEIEKRVMEAVQLQKELQQELETHVR 906
Fly 907 KEKEAEENLNKDSKQLEKWSTKENMLNEKIDECTEKIASLGAVPL-VDPSYTRMSLKNIFKELEK 970
Fly 971 ANQHLKKYNHVNKKALDQFLSFSEQKEKLYRRKEELDIGDQKIHMLIQSLEMQKVEAIQFTFRQV 1035
Fly 1036 AQNFTKVFKKLVPMGAGFLILKTKDNEGDEMEKEVENS----------------DAFTGIGIRVS 1084
Fly 1085 FTGVEAEMREMNQLSGGQKSLVALALIFSIQKCDPAPFYLFDEIDQALDAMHRKAVANMIHELSD 1149
Fly 1150 TAQFITTTFRPELLENAHKFYGVRFRNKVSHIDCVTREEAKDFVEDDSTH 1199 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SMC3 | NP_523374.2 | SMC_N | 2..1180 | CDD:280601 | 636/1198 (53%) |
| ABC_SMC3_euk | 3..>159 | CDD:213239 | 129/155 (83%) | ||
| SMC_hinge | 533..643 | CDD:214944 | 63/109 (58%) | ||
| TMPIT | 678..>760 | CDD:285135 | 25/82 (30%) | ||
| CHD5 | <780..>822 | CDD:282299 | 19/41 (46%) | ||
| P-loop_NTPase | <1088..1182 | CDD:304359 | 78/93 (84%) | ||
| SMC3 | NP_005436.1 | Smc | 1..1194 | CDD:224117 | 647/1213 (53%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 242..269 | 7/26 (27%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1059..1090 | 18/46 (39%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165156778 | |
| Domainoid | 1 | 1.000 | 1166 | 1.000 | Domainoid score | I13 |
| eggNOG | 1 | 0.900 | - | - | E1_COG1196 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H3974 | |
| Inparanoid | 1 | 1.050 | 1263 | 1.000 | Inparanoid score | I173 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54174 | |
| OrthoDB | 1 | 1.010 | - | - | D119789at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003940 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89841 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101525 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR43977 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1353 |
| SonicParanoid | 1 | 1.000 | - | - | X3237 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||