Protein Alignment SMC3 and SMC3

DIOPT Version :10

• Sequence 1: NP_523374.2
• Gene: SMC3 / 32627
• FlyBaseID: FBgn0015615
• Length: 1200
• Species: Drosophila melanogaster
• Sequence 2: NP_001190492.1
• Gene: SMC3 / 834917
• AraportID: AT5G48600
• Length: 1244
• Species: Arabidopsis thaliana
• Alignment Length: 1331
• Identity: 306/1331 - (22%)
• Similarity: 527/1331 - (39%)
• Gaps: 294/1331 - (22%)

  Fly     1 MHIKQIIIQGFKSYKDQTVVEPFDKRHNVVVGRNGSGKSNFFYAIQFVLSDEFTHLRPEQRQSLL 65
            ::||:::::.||||..:..|.||.|..:.|||.|||||||...|:.||.......:|..:...|:
plant    24 LYIKELVMRNFKSYAGEQRVGPFHKSFSAVVGPNGSGKSNVIDAMLFVFGKRAKQMRLNKVSELI 88

  Fly    66 HEGTGARVI-SAYVEIIFDNSDNRVPIDKEEIFLRRVIGA-----------KKDQYFLNKKVVPR 118
            |..|..:.: ||.|.:.|:..     ||.|......|.|:           ...:|::|::....
plant    89 HNSTNHQNLDSAGVSVQFEEI-----IDLENGLYETVPGSDFMITRVAFRDNSSKYYINERSSNF 148

  Fly   119 NEVVNLLESAGFSSSNPYYIVKQGKINQMATAA-------DSYRLKLLREVAGTRVYDERKEE-- 174
            .||...|:..|....|..:::.||::.|::...       |...|:.|.::.||..|.|:.:|
plant   149 TEVTKKLKGKGVDLDNNRFLILQGEVEQISLMKPKAQGPHDEGFLEYLEDIIGTNKYVEKIDELN 213

  Fly   175 -SLNLLRETDSKVEKISEYLKTIEDRLQTLEEEKEE--LKE--YQKWDKTRRTLEY--------- 225
             .|..|.|:.|.|.::.:..:...|.|:.|::|.|.  |||  :.||.:....:.|
plant   214 KQLETLNESRSGVVQMVKLAEKERDNLEGLKDEAETYMLKELSHLKWQEKATKMAYEDTVAKITE 278

  Fly   226 -----IRYETELKDTKKALDEL--QLQRKSSSDKK-----KIYNIEIQKAQEKIKDVQK------ 272
                 ...|..|||.:..:||.  :|::..|..:|     ::.:.|::..:||.|:.::
plant   279 QRDSLQNLENSLKDERVKMDESNEELKKFESVHEKHKKRQEVLDNELRACKEKFKEFERQDVKHR 343

  Fly   273 -NLKEAKKKVQSTKEERSVLMTEQQQLLREKTKLDLTIVDLNDEVQGDNKSKERADQELKNLKVT 336
             :||..|:|::..::          :|.::.:|    |.|:..|.:..:....:..:.:..|:..
plant   344 EDLKHVKQKIKKLED----------KLEKDSSK----IGDMTKESEDSSNLIPKLQENIPKLQKV 394

  Fly   337 IAEREKELDDVK--PKYEAMKRKEEDCSRELQLKEQKRKELYAKQGRGSQFSSRE---------- 389
            :.:.||:|:::|  .|.|....:.|......:| |...|:|...:|:....||..
plant   395 LLDEEKKLEEIKAIAKVETEGYRSELTKIRAEL-EPWEKDLIVHRGKLDVASSESELLSKKHEAA 458

  Fly   390 -----DRDKWITNELKSISKQTRDKIAHHAKLVEDLKKDATSEKDLGQKIEEHS-SELEQLRLQI 448
                 |..|    :|..||.:.::|.|.......|:|| ...|....:|:||.| .|.|.|..|.
plant   459 LKAFTDAQK----QLSDISTRKKEKAAATTSWKADIKK-KKQEAIEARKVEEESLKEQETLVPQE 518

  Fly   449 DEHNKKYYELKKT----KDQHQSMRNELWRKETQMTQQLQTHKEELSRADQALRSMAGKPILNGC 509
            ....:|..|||..    |.|::.::..|..||....:.:.....:|...|
plant   519 QAAREKVAELKSAMNSEKSQNEVLKAVLRAKENNQIEGIYGRMGDLGAID--------------- 568

  Fly   510 DSVRKVLDSFVERGGQSAEIARAYYGPVIENFSCDKTIYTAVEVTAANRLFHHIVESEYEGTQIL 574
                                  |.|...|.. :|....|..||.|:          |.....::|
plant   569 ----------------------AKYDVAIST-ACAGLDYIVVETTS----------SAQACVELL 600

  Fly   575 KEMNKLKLPGEVTFMPLNRLQVKIHDYPD---DPDSIPMISKL--KYDEQHDKALRYIFGKTLIC 634
            ::.|.    |..|||.|.:....||...:   .|:.:|.:..|  ..||:...|.....|.|::.
plant   601 RKGNL----GFATFMILEKQTDHIHKLKEKVKTPEDVPRLFDLVRVKDERMKLAFYAALGNTVVA 661

  Fly   635 RNLERATELAKSTGLD---CVTLDGDQVSSKGSLTGGYFNTSRSRLEMQKKRTEYTSQ-IAEFEK 695
            ::|::||.:|.....:   .|.|||......|:::||.......|:....:.|..:.: :|..|.
plant   662 KDLDQATRIAYGGNREFRRVVALDGALFEKSGTMSGGGGKARGGRMGTSIRATGVSGEAVANAEN 726

  Fly   696 KLSKLRNELKSTENNINSIVSEMQKTETKQGKSKDVFEKVQGEIRLMKEELVRIEQYRAPK---- 756
            :|||:.:.|    |||.                    |||...:|          ||||.:
plant   727 ELSKIVDML----NNIR--------------------EKVGNAVR----------QYRAAENEVS 757

  Fly   757 --ERSLAQCKASLESMTSTKSSLEAELKQELMSTLSSQDQREIDQLNDDIRRLNQENKEAFTQRM 819
              |..||:.:..:||:.|..:.||.:|..  :...|.....|||:|.:..:.:::|.||......
plant   758 GLEMELAKSQREIESLNSEHNYLEKQLAS--LEAASQPKTDEIDRLKELKKIISKEEKEIENLEK 820

  Fly   820 QFEVRKNKLDNLLIN------NLFRRRDELIQALQEISVEDRKRKLNNCKTELVSAEKRIKKVNS 878
            ..:..|:|...|..|      ...:.:...::.:| ..::....::|.|..::.:.:|.|||:..
plant   821 GSKQLKDKALELQTNIENAGGEKLKGQKAKVEKIQ-TDIDKNNTEINRCNVQIETNQKLIKKLTK 884

  Fly   879 DLEEIEKRVMEAVQLQKE-LQQELETHVRKEKEAEENLNKDSKQLEKW--------STKENMLNE 934
            .:|| ..|..|.::.:|| |....:...:|..|.:|...|..:.:::.        |..|| |.:
plant   885 GIEE-ATREKERLEGEKENLHVTFKDITQKAFEIQETYKKTQQLIDEHKDVLTGAKSDYEN-LKK 947

  Fly   935 KIDECTEKIASLGAVPLVDPSYTRMSLKNIFKELEKANQHLKKY--------------------- 978
            .:||.        ....||..:....:|..:.|||...:..||.
plant   948 SVDEL--------KASRVDAEFKVQDMKKKYNELEMREKGYKKKLNDLQIAFTKHMEQIQKDLVD 1004

  Fly   979 ----------NHVN-----KKALDQFLSFSEQKEKL---------YRRKEELDIGDQKIHMLIQS 1019
                      |::|     |:||:.......|.::|         ||.|.||..|        :.
plant  1005 PDKLQATLMDNNLNEACDLKRALEMVALLEAQLKELNPNLDSIAEYRSKVELYNG--------RV 1061

  Fly  1020 LEMQKVEAIQFTFRQVAQNFTKVFKKLVPMGAGFLILKTKDNE-------GDEMEKE-VENSDAF 1076
            .|:..|...:...|:......|  ::|....|||..:..|..|       |.:.|.| |::.|.|
plant  1062 DELNSVTQERDDTRKQYDELRK--RRLDEFMAGFNTISLKLKEMYQMITLGGDAELELVDSLDPF 1124

  Fly  1077 TGIGIRVSFTGVEAEMREMNQLSGGQKSLVALALIFSIQKCDPAPFYLFDEIDQALDAMHRKAVA 1141
            :. |:..|....:...:.:..||||:|:|.:|||:|::....|.|.|:.||||.|||..:...|.
plant  1125 SE-GVVFSVRPPKKSWKNIANLSGGEKTLSSLALVFALHHYKPTPLYVMDEIDAALDFKNVSIVG 1188

  Fly  1142 NMIHELSDTAQFITTTFRPELLENAHKFYGV 1172
            :.:.:.:..||||..:.|..:.|.|.:..|:
plant  1189 HYVKDRTKDAQFIIISLRNNMFELADRLVGI 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC3	NP_523374.2	SMC_N	2..1180	CDD:426784	306/1330 (23%)
SMC3	NP_001190492.1	SMC_N	25..1228	CDD:426784	306/1330 (23%)