Protein Alignment SMC3 and ATSMC2

DIOPT Version :10

• Sequence 1: NP_523374.2
• Gene: SMC3 / 32627
• FlyBaseID: FBgn0015615
• Length: 1200
• Species: Drosophila melanogaster
• Sequence 2: NP_001325474.1
• Gene: ATSMC2 / 823900
• AraportID: AT3G47460
• Length: 1174
• Species: Arabidopsis thaliana
• Alignment Length: 1309
• Identity: 338/1309 - (25%)
• Similarity: 586/1309 - (44%)
• Gaps: 258/1309 - (19%)

  Fly     1 MHIKQIIIQGFKSYKDQTVVEPFDKRHNVVVGRNGSGKSNFFYAIQFVLS-DEFTHLRPEQRQSL 64
            ||||:|.::|||||..:|||..||...|.:.|.|||||||...:|.|||. .....:|....|.|
plant     1 MHIKEICLEGFKSYATRTVVPGFDPHFNAITGLNGSGKSNILDSICFVLGITNLQQVRAANLQEL 65

  Fly    65 LHEGTGARVISAYVEIIFDNSD-NRVPI---DKEEIFL-RRVIGAKKDQYFLNKKVVPRNEVVNL 124
            :::...|.:..|.|.:.||||: ||.|:   |..||.: |:::...|::|.:|.|:...|:|.||
plant    66 VYKQGQAGITRATVSVTFDNSERNRSPLGHEDHSEITVTRQIVVGGKNKYLINGKLAQPNQVQNL 130

  Fly   125 LESAGFSSSNPYYIVKQGKINQMATAADSYRLKLLREVAGTRVYDERKEESLNLLRETDSKVEKI 189
            ..|...:.:||::::.||:|.::........|.:|.|.||||:|:.:||.:|..|.:..:||::|
plant   131 FHSVQLNVNNPHFLIMQGRITKVLNMKPMEILSMLEEAAGTRMYENKKEAALKTLEKKQTKVDEI 195

  Fly   190 SEYLKTIEDRLQTLEEEKEELKEYQKW-------DKTRR---TLEYIRYETELKDTKKALDELQL 244
            ::.|:  :|.|..||:.:.|..:|.:|       |:.:|   ..||::.|....::...::|:::
plant   196 NKLLE--KDILPALEKLRREKSQYMQWANGNAELDRLKRFCVAFEYVQAEKIRDNSIHVVEEMKI 258

  Fly   245 QRKSSSDKKKIYNIEIQ--KAQEKIKDVQKNLKE-AKKKVQSTKEERSVLMTEQQQLLREKTKLD 306
                     |:..|:.|  |.|.:|.:::|.:|. .:.:..|...|...|..:...|..|.|:..
plant   259 ---------KMTGIDEQTDKTQGEISELEKQIKALTQAREASMGGEVKALSDKVDSLSNEVTREL 314

  Fly   307 LTIVDLNDEVQGDNKSKERADQELKNLKVTIAEREKELD-------DVKPKYEAMKRKEEDCSRE 364
            ..:.::.|.:||:.|:.|:....:::||.::.||...|:       ::|.|::......|:|.||
plant   315 SKLTNMEDTLQGEEKNAEKMVHNIEDLKKSVEERASALNKCDEGAAELKQKFQEFSTTLEECERE 379

  Fly   365 LQLKEQKRKELYAKQGRGSQFSSRED--RDKWIT-----NELKSISKQTRDKIAHHAKLVEDLKK 422
            .|       .:.|.:..|.:....||  ||..|:     .||    ||...||:|..|.:::.|.
plant   380 HQ-------GILAGKSSGDEEKCLEDQLRDAKISVGTAETEL----KQLNTKISHCEKELKEKKS 433

  Fly   423 DATSEKDLGQKIEEHSSELEQLRLQIDEHNKKYYELKKTKDQHQSMRNELWRKETQMTQQLQTHK 487
            ...|::|....:|   :||:..:..::...:.:..|...:.|.:::..:. ..|.::..:|:...
plant   434 QLMSKQDEAVAVE---NELDARKNDVESVKRAFDSLPYKEGQMEALEKDR-ESELEIGHRLKDKV 494

  Fly   488 EELSRADQALRSMAGKPILNGCDSVRKVLDSFVERGGQSAEIARAYYGPVIENFS---------- 542
            .|||                                .|.|.:...|..|| :||.
plant   495 HELS--------------------------------AQLANVQFTYRDPV-KNFDRSKVKGVVAK 526

  Fly   543 ----CDKTIYTAVEVTAANRLFHHIVESEYEGTQILKEMNKLKLPGEVTFMPLNRLQVKIHDYPD 603
                .|::..||:||||..:||:.||::|..|.|:|:   |..|...||.:|||::|..:.....
plant   527 LIKVNDRSSMTALEVTAGGKLFNVIVDTEDTGKQLLQ---KGDLRRRVTIIPLNKIQSHLVPPRV 588

  Fly   604 DPDSIPMISK---------LKYDEQHDKALRYIFGKTLICRNLERATELA--KSTGLDCVTLDGD 657
            ...::.::.|         :.|.|:...|:.|:||.|.:|:..:.|.|:|  :......|||:||
plant   589 QQATVKLVGKGNAELALSLVGYSEELKNAMEYVFGSTFVCKTTDAAKEVAFNREIRTPSVTLEGD 653

  Fly   658 QVSSKGSLTGG--------------------YFNTSRSRL--------EMQKKRTEYTSQIAEFE 694
            .....|.||||                    .|...:..|        |:|..:|::|...|:.|
plant   654 VFQPSGLLTGGSRKGGGDLLRQLHDLAEAETKFRAHQKSLSEIEANIKELQPLQTKFTDMKAQLE 718

  Fly   695 KKLSKLRNELKSTENNINSIVSEMQKTETKQGKSKDVFEKVQGEIRLMKEELVRIEQYRAPKERS 759
            .|:..:...||..|.|             :..|..|..:|::.|:..|:.::         ||:
plant   719 LKMYDMSLFLKRAEQN-------------EHHKLGDAVKKLEEEVEEMRSQI---------KEK- 760

  Fly   760 LAQCKASLESMTSTKSSLEAELK-------------QELMSTLSSQDQREIDQL--NDDIRRLNQ 809
                :...:|...|.|:||..:|             ::.:.||.::.|.....|  ::::|....
plant   761 ----EGLYKSCADTVSTLEKSIKDHDKNREGRLKDLEKNIKTLKARIQASSKDLKGHENVRERLV 821

  Fly   810 ENKEAFTQRMQFEVRKNKLDNL--LINNLF------RRRDELIQALQEISVEDRK---RKLNNCK 863
            ..:||.||...:  .|::|.:|  .|:.|.      |.:.:.||...:.|:.:.|   .|:..|.
plant   822 MEQEAVTQEQSY--LKSQLTSLRTQISTLASDVGNQRAKVDAIQKDHDQSLSELKLIHAKMKECD 884

  Fly   864 TE----LVSAEKRIKKVNSDLEEIEKRVMEAVQLQKELQQELETHVRKEKEAEENLNKDSKQLEK 924
            |:    :...||.::|: ||: ::::         |:|:.|:   .|.|.|.:....|..|.:||
plant   885 TQISGSIAEQEKCLQKI-SDM-KLDR---------KKLENEV---TRMEMEHKNCSVKVDKLVEK 935

  Fly   925 --WSTKENML--NEKIDECTEKIASLGAVPLVDPSYTRMSLKNIFKELEKANQHLKKYNHVNKKA 985
              |.|.|..|  |...|...|.         .||...|..|    :.|:.....|:|  .||||.
plant   936 HTWITSEKRLFGNGGTDYDFES---------RDPHKAREEL----ERLQTDQSSLEK--RVNKKV 985

  Fly   986 LDQFLSFSEQKEKLYRRKEELDIGDQKIHMLIQSLEMQKVEAIQFTFRQVAQNFTKVFKKLVPMG 1050
            ...|....::...|..:|..::....||..:|:.|:.:|.|.::.|:.:|.|:|..:|..|:|
plant   986 TAMFEKAEDEYNALMTKKNIIETDKSKIKKVIEELDEKKKETLKVTWVKVNQDFGSIFSTLLP-- 1048

  Fly  1051 AGFLILKTKDNEGDEMEKEVENSDAF-TGIGIRVSFTGVEAEMREMNQLSGGQKSLVALALIFSI 1114
                        |...:.|......| .|:.:||:|..|..:  .:::|||||:||:||:||.::
plant  1049 ------------GTMSKLEPPEGGTFLDGLEVRVAFGDVWKQ--SLSELSGGQRSLLALSLILAL 1099

  Fly  1115 QKCDPAPFYLFDEIDQALDAMHRKAVANMIHELSDTAQFITTTFRPELLENAHKFYGVRFRNKVS 1179
            ....|||.|:.||:|.|||..|.:.:..||......:|||..:.:..:..||...:..:|.:.||
plant  1100 LLFKPAPIYILDEVDAALDLSHTQNIGRMIKSHFPHSQFIVVSLKEGMFSNADVLFRTKFVDGVS 1164

  Fly  1180 HID-CVTRE 1187
            .:. .||::
plant  1165 TVQRTVTKQ 1173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC3	NP_523374.2	SMC_N	2..1180	CDD:426784	334/1298 (26%)
ATSMC2	NP_001325474.1	SMC_N	2..1165	CDD:481474	334/1298 (26%)