Protein Alignment SMC3 and TTN7

DIOPT Version :10

• Sequence 1: NP_523374.2
• Gene: SMC3 / 32627
• FlyBaseID: FBgn0015615
• Length: 1200
• Species: Drosophila melanogaster
• Sequence 2: NP_180285.4
• Gene: TTN7 / 817259
• AraportID: AT2G27170
• Length: 1204
• Species: Arabidopsis thaliana
• Alignment Length: 1224
• Identity: 485/1224 - (39%)
• Similarity: 775/1224 - (63%)
• Gaps: 47/1224 - (3%)

  Fly     1 MHIKQIIIQGFKSYKDQTVVEPFDKRHNVVVGRNGSGKSNFFYAIQFVLSDEFTHLRPEQRQSLL 65
            |.|||:||:||||||:|...|.|..:.|.|||.|||||||||:||:|||||.:.:||.|.|.:||
plant     1 MFIKQVIIEGFKSYKEQVATEEFSNKVNCVVGANGSGKSNFFHAIRFVLSDIYQNLRSEDRHALL 65

  Fly    66 HEGTGARVISAYVEIIFDNSDNRVPIDKEEIFLRRVIGAKKDQYFLNKKVVPRNEVVNLLESAGF 130
            |||.|.:|:||:|||:|||||||.|:|||||.|||.:|.|||.|||:.|.:.:.||:||||||||
plant    66 HEGAGHQVVSAFVEIVFDNSDNRFPVDKEEIRLRRTVGLKKDDYFLDGKHITKGEVMNLLESAGF 130

  Fly   131 SSSNPYYIVKQGKINQMATAADSYRLKLLREVAGTRVYDERKEESLNLLRETDSKVEKISEYLKT 195
            |.:||||:|:||||..:....|..||.||:|:.|||||:||:.|||.:::||.:|.::|.|.:..
plant   131 SRANPYYVVQQGKIASLTLMKDIERLDLLKEIGGTRVYEERRRESLRIMQETGNKRKQIIEVVHY 195

  Fly   196 IEDRLQTLEEEKEELKEYQKWDKTRRTLEYIRYETELKDTKKALDELQLQR-KSSSDKKKIYNIE 259
            :::||:.|:||||||::||:.||.|::|||..|:.||.|.::.|:::::.| |:|.:..|:|: .
plant   196 LDERLRELDEEKEELRKYQQLDKQRKSLEYTIYDKELHDAREKLEQVEVARTKASEESTKMYD-R 259

  Fly   260 IQKAQEKIKDVQKNLKEAKKKVQSTKEERSVLMTEQQQLLREKTKLDLTIVDLNDEVQGDNKSKE 324
            ::|||:..|.:.::|||..|::|:..:|:..:..:|.:.|::||||:|.:.|..|.:.|:.:||.
plant   260 VEKAQDDSKSLDESLKELTKELQTLYKEKETVEAQQTKALKKKTKLELDVKDFQDRITGNIQSKN 324

  Fly   325 RADQELKNLKVTIAEREKELDDVKPKYEAMKRKEEDCSRELQLKEQKRKELYAKQGRGSQFSSRE 389
            .|.::|..::..:.:..:||:.:||.||:...||...|:.:...|:....||.||||.:|||::.
plant   325 DALEQLNTVEREMQDSLRELEAIKPLYESQVDKENQTSKRINELEKTLSILYQKQGRATQFSNKA 389

  Fly   390 DRDKWITNELKSISKQTRDKIAHHAKLVEDLKKDATSEKDLGQKIEEHSSELEQLRLQIDEHNKK 454
            .||||:..|::.:.:..........||.:::.:..|...:..:.|::|..|:.:|..:|.:.::.
plant   390 ARDKWLRKEIEDLKRVLDSNTVQEQKLQDEILRLNTDLTERDEHIKKHEVEIGELESRISKSHEL 454

  Fly   455 YYELKKTKDQHQSMRNELWRKETQMTQQLQTHKEELSRADQALRSMAGKPILNGCDSVRKVLDSF 519
            :...|:.:|:.|..|.|.|.:|:|::.::...|.||.||.:.|.......:..|.:|:|::...:
plant   455 FNTKKRERDEEQRKRKEKWGEESQLSSEIDKLKTELERAKKNLDHATPGDVRRGLNSIRRICADY 519

  Fly   520 VERGGQSAEIARAYYGPVIENFSCDKTIYTAVEVTAANRLFHHIVESEYEGTQILKEMNKLKLPG 584
            ...|         .:||::|...||:..:|||||||.|.||:.:||::...|:|::.:|.|| .|
plant   520 RING---------VFGPLVELVDCDEKFFTAVEVTAGNSLFNVVVENDDISTKIIRHLNSLK-GG 574

  Fly   585 EVTFMPLNRLQVKIHDYPDDPDSIPMISKLKYDEQHDKALRYIFGKTLICRNLERATELAKSTGL 649
            .|||:||||::....:||.|.|:||::.|||:|.:.:.||..:||:|::||:|..||.:||:..|
plant   575 RVTFLPLNRIKAPRVNYPKDSDAIPLLKKLKFDSKFEPALGQVFGRTVVCRDLNVATRVAKNDDL 639

  Fly   650 DCVTLDGDQVSSKGSLTGGYFNTSRSRLEMQKKRTEYTSQIAEFEKKLSKLRNELKSTENNINSI 714
            ||:|::|||||.||.:|||:::..||:|.......:.|..|.|.||:|..:|.:|:..:..|..:
plant   640 DCITMEGDQVSRKGGMTGGFYDHRRSKLRFMNIIMQNTKSINEKEKELEDVRRQLQVIDQQITQL 704

  Fly   715 VSEMQKTETKQGKSKDVFEKVQGEIRLMKEELVRIEQYRAPKERSLAQCKASLESMTSTKSSLEA 779
            |:|.|:.|......|...|:::.||....::...|.:....||:.|...:..::.:.|:.|..||
plant   705 VTEQQRLEADWTLCKLQVEQLKQEIANANKQKHAIHKAIEYKEKLLGDIRTRIDQVRSSMSMKEA 769

  Fly   780 ELKQELMSTLSSQDQREIDQLNDDIRRLNQENKEAF-TQRMQFEVRKNKLDNLLINNLFRRRDEL 843
            |:..||:..|:.:::.::.:||.:|:.| :|.|.|: ..|::.|.||.:|:..:..||.||..||
plant   770 EMGTELVDHLTPEEREQLSKLNPEIKDL-KEKKFAYQADRIERETRKAELEANIATNLKRRITEL 833

  Fly   844 IQALQEI-------SVEDRKRKLNNCKTELVSAEKRIKKVNSDLEEIEKRVMEAVQLQKELQQEL 901
            ...:..|       |...::::|::.|..:..|.|.:|.|...::|..|::.:.    |:.:.:|
plant   834 QATIASIDDDSLPSSAGTKEQELDDAKLSVNEAAKELKSVCDSIDEKTKQIKKI----KDEKAKL 894

  Fly   902 ETHVRKEKEAEENLNKDSKQLEKWSTKENMLNEKIDECTEKIASLGAVPLVD---PSYTRMSLKN 963
            :|   .|.:.:..|....|:||:..:..|.|..|.||.|:||..||  ||..   .:|.|.::|.
plant   895 KT---LEDDCKGTLQDLDKKLEELFSLRNTLLAKQDEYTKKIRGLG--PLSSDAFDTYKRKNIKE 954

  Fly   964 IFKELEKANQHLKKYNHVNKKALDQFLSFSEQKEKLYRRKEELDIGDQKIHMLIQSLEMQKVEAI 1028
            :.|.|.:.::.|::::|||||||||:::|:||:|:|..|:.|||.||:||..||..|:.:|.|:|
plant   955 LQKMLHRCSEQLQQFSHVNKKALDQYVNFTEQREELQNRQAELDAGDEKIKELITVLDQRKDESI 1019

  Fly  1029 QFTFRQVAQNFTKVFKKLVPMGAG-FLILKTKDNEGDEMEKEVENS----------DAFTGIGIR 1082
            :.||:.||.:|..||.:||..|.| .:|:|.||.:.|:.:.:.::.          :.:.|:.::
plant  1020 ERTFKGVAHHFRDVFSELVQDGYGNLIIMKKKDLDNDDEDDDDDDGGREAVTEGRVEKYIGVKVK 1084

  Fly  1083 VSFTGVEAEMREMNQLSGGQKSLVALALIFSIQKCDPAPFYLFDEIDQALDAMHRKAVANMIHEL 1147
            ||||| :.|.:.|.|||||||::|||||||:||:|||||||||||||.|||..:|.||.|:|..|
plant  1085 VSFTG-QGETQLMKQLSGGQKTVVALALIFAIQRCDPAPFYLFDEIDAALDPQYRTAVGNLIRRL 1148

  Fly  1148 SDT--AQFITTTFRPELLENAHKFYGVRFRNKVSHIDCVTREEAKDFVEDDSTH 1199
            :|.  .|||||||||||:..|.|.|||..:|:||.::.:::::|.||:|.|.:|
plant  1149 ADDYGTQFITTTFRPELVRVADKIYGVFHKNRVSIVNVISKDQALDFIEKDQSH 1202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC3	NP_523374.2	SMC_N	2..1180	CDD:426784	477/1202 (40%)
TTN7	NP_180285.4	SMC_N	2..1175	CDD:481474	473/1194 (40%)