Protein Alignment CG33160 and PLAT

DIOPT Version :10

• Sequence 1: NP_788456.1
• Gene: CG33160 / 326265
• FlyBaseID: FBgn0053160
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 74/267 - (27%)
• Similarity: 114/267 - (42%)
• Gaps: 50/267 - (18%)

  Fly    22 YAHPDSVQIQPRIIGGHVSSIKEEKYLVQVTTSEE-------LCGGSLVKPRWVITAAHCVYNKN 79
            |:.|     |.||.||..:.|....:...:.....       ||||.|:...|:::||||...:.
Human   304 YSQP-----QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERF 363

  Fly    80 K---------NDFKIYGGASNQAGPYAVIRTVDYIAIRPDFNRKTLNMDVAALRLNSDMIGANIE 135
            .         ..:::..|...|.     .....|| :..:|:..|.:.|:|.|:|.||......|
Human   364 PPHHLTVILGRTYRVVPGEEEQK-----FEVEKYI-VHKEFDDDTYDNDIALLQLKSDSSRCAQE 422

  Fly   136 T-------IPLAAQSVPARALVKVSGWGFLTADATKTAERVHSVLVPMWSRASCVSAFRGIHRIT 193
            :       :|.|...:|.....::||:|...|.:...:||:....|.::..:.|.|.......:|
Human   423 SSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVT 487

  Fly   194 RSMVCA---------ARLYKKDSCDGDSGGPLVY----RGQLAGIVSFGYGCASA-LPGIYTSVP 244
            .:|:||         |.|:  |:|.||||||||.    |..|.||:|:|.||... :||:||.|.
Human   488 DNMLCAGDTRSGGPQANLH--DACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVT 550

  Fly   245 EIRDWFQ 251
            ...||.:
Human   551 NYLDWIR 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	69/252 (27%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	69/253 (27%)