Protein Alignment CG33160 and KLK12

DIOPT Version :10

• Sequence 1: NP_788456.1
• Gene: CG33160 / 326265
• FlyBaseID: FBgn0053160
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 70/245 - (28%)
• Similarity: 114/245 - (46%)
• Gaps: 20/245 - (8%)

  Fly     6 LTSLFLVQILGFHSAVYAHPDSVQIQPRIIGGHVSSIKEEKYLVQVTTSEEL-CGGSLVKPRWVI 69
            |:...|:.:||...|.         .|:|..|.......:.:.|.:.....| |||.|:..|||:
Human     3 LSIFLLLCVLGLSQAA---------TPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVL 58

  Fly    70 TAAHCVYNKNKNDFKIYGGASNQAGPYAVIRTVDYIAIRPDFNRKTLN--MDVAALRLNSDM-IG 131
            |||||  :.::...::...:.:|......||...:....|.:...:.:  .|:..|||...: :.
Human    59 TAAHC--SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121

  Fly   132 ANIETIPLAAQSVPARALVKVSGWGFLTADATKTAERVHSVLVPMWSRASCVSAFRGIHRITRSM 196
            ::::.:||......|.....|||||..........:.:..:.:.:.|.|:|...:.|  |||.:|
Human   122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPG--RITSNM 184

  Fly   197 VCAARLYKKDSCDGDSGGPLVYRGQLAGIVSFGY--GCA-SALPGIYTSV 243
            |||..:..:|:|.||||||||..|.|.|:||:|.  .|. ..:||:||.:
Human   185 VCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	64/218 (29%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	64/217 (29%)