DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33160 and ea

DIOPT Version :9

Sequence 1:	NP_788456.1	Gene:	CG33160 / 326265	FlyBaseID:	FBgn0053160	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	288	Identity:	85/288 - (29%)
Similarity:	120/288 - (41%)	Gaps:	88/288 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 RIIGGHVSSIKEEKY--LVQVTTSE----ELCGGSLVKPRWVITAAHCVYNKN-KNDFKIYG--- 87
            ||.||..:.|.|..:  |::.|.|:    ..|||||:..|:||||:|||..|. ..|:::.|
  Fly   127 RIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRL 191

  Fly    88 ----------------GASNQAGPY---AVIRTVDYIAIRPDFNRKTLNM--DVAALRLNSDMIG 131
                            |..:.|.|:   .|.||:.:    ||:...:.|.  |:|.|||     .
  Fly   192 GEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPH----PDYIPASKNQVNDIALLRL-----A 247

  Fly   132 ANIE--------TIPLAAQSVPARA------LVKVSGWGFLTADATKTAERVHSVLVPMWSRASC 182
            ..:|        .:||   .|..|:      .:.|:|||       ||.:...|.|    ...:.
  Fly   248 QQVEYTDFVRPICLPL---DVNLRSATFDGITMDVAGWG-------KTEQLSASNL----KLKAA 298

  Fly   183 VSAFR-----GIHR-----ITRSMVCAARLYKKDSCDGDSGGPLVYRGQ--------LAGIVSFG 229
            |..||     .::.     :..:.:||......|||.|||||||:....        |||:||||
  Fly   299 VEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFG 363

  Fly   230 -YGCASA-LPGIYTSVPEIRDWFQRVVE 255
             ..|..| .||:||.|.:..||.|..:|
  Fly   364 PTPCGLAGWPGVYTLVGKYVDWIQNTIE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	81/280 (29%)
CG33160	NP_788456.1	Tryp_SPc	34..253	CDD:238113	83/283 (29%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	82/281 (29%)
		Tryp_SPc	128..389	CDD:238113	83/283 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010