Protein Alignment CG33160 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_788456.1
• Gene: CG33160 / 326265
• FlyBaseID: FBgn0053160
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 84/283 - (29%)
• Similarity: 121/283 - (42%)
• Gaps: 73/283 - (25%)

  Fly    23 AHPDSVQIQP--------RIIGGHVS-----------SIKEEKYLVQVTTSEELCGGSLVKPRWV 68
            ||.:.....|        |||||..:           .||..:.||.|      |||:||:.|||
Human    59 AHAEDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHV------CGGTLVRERWV 117

  Fly    69 ITAAHCVYNKNKNDFKIYG---GASNQAGPYAVIRTVDY--IAIRPDFNRKTLNMDVA------A 122
            :|||||  .|:.:|..::.   |.:|..|.|...:.:..  |.|.|:|..::...|:|      |
Human   118 LTAAHC--TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA 180

  Fly   123 LRLNSDMIGANIETIPL---AAQSVPARALVKVSGWGFLTADATKT-----AERVHSVLVPMWSR 179
            :|.|.     .|:.|.|   ..|.:.......:||||....:...|     || ||.:     ||
Human   181 VRYND-----YIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAE-VHYI-----SR 234

  Fly   180 ASCVS--AFRGIHRITRSMVCAA-RLYKKDSCDGDSGGPLV------YRGQLAGIVSFGYGCA-S 234
            ..|.|  ::.||  |..:..||. .....|:|.|||||||:      .|..:.||.|:|:||. .
Human   235 EMCNSERSYGGI--IPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRR 297

  Fly   235 ALPGIYTSVPEIRDWFQRVVEQH 257
            ..||:|..    ..::|:.:.:|
Human   298 GFPGVYIG----PSFYQKWLTEH 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	79/255 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	79/262 (30%)