Protein Alignment CG33160 and F10

DIOPT Version :10

• Sequence 1: NP_788456.1
• Gene: CG33160 / 326265
• FlyBaseID: FBgn0053160
• Length: 258
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 83/265 - (31%)
• Similarity: 120/265 - (45%)
• Gaps: 57/265 - (21%)

  Fly    26 DSVQIQP--------RIIGGHVSS----------IKEEKYLVQVTTSEELCGGSLVKPRWVITAA 72
            |..|.||        ||:||....          |.||        :|..|||:::...:::|||
Human   219 DFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEE--------NEGFCGGTILSEFYILTAA 275

  Fly    73 HCVYNKNKNDFKIYGGASN---QAGPYAVIRTVDYIAIRPDFNRKTLNMDVAALRLNSDM-IGAN 133
            ||:|...:  ||:..|..|   :.|..|| ..|:.:.....|.::|.:.|:|.|||.:.: ...|
Human   276 HCLYQAKR--FKVRVGDRNTEQEEGGEAV-HEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMN 337

  Fly   134 IETIPLAAQSVPARALVK----------VSGWGFLTADATKTAERVHSVLVPMWSRASCVSAFRG 188
            :     |...:|.|...:          |||:| .|.:..:.:.|:..:.||...|.||..:...
Human   338 V-----APACLPERDWAESTLMTQKTGIVSGFG-RTHEKGRQSTRLKMLEVPYVDRNSCKLSSSF 396

  Fly   189 IHRITRSMVCAARLYK-KDSCDGDSGGPLVYRGQ----LAGIVSFGYGCA-SALPGIYTSVPEIR 247
            |  ||::|.||....| :|:|.||||||.|.|.:    :.||||:|.||| ....||||.|....
Human   397 I--ITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFL 459

  Fly   248 DWFQR 252
            .|..|
Human   460 KWIDR 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	77/245 (31%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	77/247 (31%)
		O-glycosylated at one site	476..485