DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33160 and f12

DIOPT Version :9

Sequence 1:	NP_788456.1	Gene:	CG33160 / 326265	FlyBaseID:	FBgn0053160	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	241	Identity:	75/241 - (31%)
Similarity:	112/241 - (46%)	Gaps:	21/241 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 IQPRIIGGHVSSIKEEKYLVQVTTSEELCGGSLVKPRWVITAAHCVYNK-NKNDFKIYGGAS--N 91
            |.|||:||.|:......|:..:......|||||:.|.|::|||||:..: |.....:..|.|  |
Frog   355 IMPRIVGGLVALPASHPYIAALYIDNHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVLGQSRFN 419

  Fly    92 QAGPYAVIRTVDYIAIRPDFNRKTLNMDVAALRLNS------DMIGANIETIPLAAQSVPARALV 150
            ....:.|...|:...:...:...||..|:|.:::.|      ......::.|.|..|...|.:..
Frog   420 TTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAESTK 484

  Fly   151 K--VSGWGFLTADATKTAERVHSVLVPMWSRASCVSAFRGIH--RITRSMVCAARLY-KKDSCDG 210
            :  |:|||.....|...|..:....:|:.....|.|.  .:|  |:...|:||..:. ..|:|.|
Frog   485 QCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQCQSP--SVHGDRMLPGMLCAGFMEGGVDACQG 547

  Fly   211 DSGGPLVY----RGQLAGIVSFGYGCASA-LPGIYTSVPEIRDWFQ 251
            |||||||.    |.:|.|:||:|.|||.. .||:||:|....||.:
Frog   548 DSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWIR 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33160	NP_788456.1	Tryp_SPc	33..249	CDD:214473	71/234 (30%)
CG33160	NP_788456.1	Tryp_SPc	34..253	CDD:238113	72/237 (30%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	72/237 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910