Protein Alignment AGBE and Gbe1

DIOPT Version :10

• Sequence 1: NP_788342.1
• Gene: AGBE / 326264
• FlyBaseID: FBgn0053138
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_083079.1
• Gene: Gbe1 / 74185
• MGIID: 1921435
• Length: 702
• Species: Mus musculus
• Alignment Length: 683
• Identity: 422/683 - (61%)
• Similarity: 523/683 - (76%)
• Gaps: 6/683 - (0%)

  Fly     1 MAEAKDIEKLFETDGYLRPFEHEIRRRHGVLEDWLNKINQSEGGLDGFSTAYKHYGLHFQPDNSV 65
            :|:..::.:|.|.|.||:||..:.:||:......|:.|.::|||:|.||..|:.:|:|...|..:
Mouse    22 LADVPELARLLEIDPYLKPFAADFQRRYKKFSQVLHDIGENEGGIDKFSRGYESFGIHRCSDGGI 86

  Fly    66 IAREWAPGARDVYLTGDFNNWHWESHPFKKLDFGKWELHLPPNEDGSPAIKHLSEIKIIIRNHSG 130
            ..:||||||..|:|||:|:.|:..|||:|||::|||||::||.::.||.|.|.|::|::|.:.||
Mouse    87 YCKEWAPGAEGVFLTGEFSGWNPFSHPYKKLEYGKWELYIPPKQNKSPLIPHGSKLKVVITSKSG 151

  Fly   131 QLLDRLSPWAKYVVQPPKSANQGVNYKQYVWEPPSYERYQRQHPGPPRPKSLRIYECHVGIASQE 195
            ::|.|:||||||||:    .|..|||....|.|.  :.|:.:|..|.:|:||||||.||||:|.|
Mouse   152 EILYRISPWAKYVVR----ENNNVNYDWIHWAPE--DPYKFKHSRPKKPRSLRIYESHVGISSHE 210

  Fly   196 PRVGSYDEFADRIVPRIKRQGYNCIQVMAIMEHAYYASFGYQVTSFYAASSRYGNPEQLKRMIDV 260
            .::.||..|...::||||..||||||:|||||||||||||||:|||:|||||||.||:||.::|.
Mouse   211 GKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELKELVDT 275

  Fly   261 AHSHGLFVLLDVVHSHASKNVQDGLNQFDGTNSCFFHDGARGEHSLWDSRLFNYVEYEVLRFLLS 325
            |||.|:.|||||||||||||.:||||.||||:||:||.|.||.|.|||||||.|..:||||||||
Mouse   276 AHSMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGPRGTHDLWDSRLFIYSSWEVLRFLLS 340

  Fly   326 NLRWWHDEYNFDGYRFDGVTSMLYHSRGIGEGFSGDYNEYFGLNVDTDALNYLGLANHLLHTIDS 390
            |:|||.:||.|||:|||||||||||..|:|:||||||||||||.||.|||.||.|||||.||:..
Mouse   341 NIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQGFSGDYNEYFGLQVDEDALIYLMLANHLAHTLYP 405

  Fly   391 RIITIAEDVSGMPTLCRPVSEGGIGFDYRLGMAIPDKWIELLKEQSDDEWDMGNLVHTLTNRRWM 455
            ..|||||||||||.||.|.|:||.||||||.||||||||:||||..|::|:|||:|:||||||::
Mouse   406 DSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRYL 470

  Fly   456 ENTVAYAESHDQALVGDKTIAFWLMDKEMYTHMSTLSDSSVIIDRGLALHKMIRLITHALGGEAY 520
            |..||||||||||||||||:||||||.||||:||.|:..:.:||||:.||||||||||.||||.|
Mouse   471 EKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGY 535

  Fly   521 LNFMGNEFGHPEWLDFPRVGNNDSYHYARRQWNLVDDDLLKYKYLNEFDRAMNEAEERYGWLHSG 585
            ||||||||||||||||||.|||:||||||||:||.|||||:||:||.|||.||..|||.|||.:.
Mouse   536 LNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEERCGWLSAP 600

  Fly   586 PAWVSWKHEGDKIIAFERAGLVFVFNFHPQQSFTGYRVGTNWAGTYQAVLSSDDPLFGGHNRIDA 650
            .|:||.|||.:|.|.||||||:|:|||||.:|:|.|||||...|.::.||.||...:|||.|:|.
Mouse   601 QAYVSEKHEANKTITFERAGLLFIFNFHPSKSYTDYRVGTATPGKFKIVLDSDAAEYGGHQRLDH 665

  Fly   651 NCKHPSNPEGYAGRSNFIEVYTPSRTAVVYARV 683
            |..:.:....:.||...:.||.|||.|::...|
Mouse   666 NTNYFAEAFEHNGRPYSLLVYIPSRVALILQNV 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AGBE	NP_788342.1	PLN02447	9..685	CDD:215246	421/675 (62%)
Gbe1	NP_083079.1	PLN02447	30..699	CDD:215246	421/675 (62%)