DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AGBE and aah3

DIOPT Version :9

Sequence 1:	NP_788342.1	Gene:	AGBE / 326264	FlyBaseID:	FBgn0053138	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_587976.1	Gene:	aah3 / 2539415	PomBaseID:	SPCC63.02c	Length:	564	Species:	Schizosaccharomyces pombe

Alignment Length:	425	Identity:	87/425 - (20%)
Similarity:	140/425 - (32%)	Gaps:	143/425 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 IKRQGYNCIQVMAI-------MEHAYYASFGYQVTSFYAASSRYGNPEQLKRMIDVAHSHGLFVL 269
            |:..|:|.|.:..|       ::.|.||..||..|.:.:.:..:|..:.|..:|..||..|::|:
pombe    73 IEDMGFNAIWISPIDKNIEGDIDGAGYAYHGYWNTDYESLNEHFGTEDDLVSLITAAHKAGIWVM 137

  Fly   270 LD-VVHSHA-SKNVQD----GLNQFDGTNSCFFH----------DGARGEHSLW-DSRL----FN 313
            || :|:|.| :..:.|    .||.|:  ...:||          |........| ||.:    .:
pombe   138 LDSIVNSMALAPPLADADYSSLNPFN--KESYFHPYCLIDWDITDNETNVMDCWQDSGVLLADLD 200

  Fly   314 YVEYEVLRFLLSNLRWWHDEYNFDGYRFDGVTSMLY-------HSRG---IGEGFSGD------- 361
            ....:|..:|..:.:....:|:|||.|.|.|..|.|       .:.|   :||.||.|
pombe   201 VESSDVSSYLSDHFKSLISKYDFDGLRIDAVKMMNYTFFPDFVDATGVYSVGEVFSYDPDTMCSY 265

  Fly   362 --------------------------------YNEYFGLNVD--TDALNYLGLANHLL-----HT 387
                                            |.|....|..  ...|....:.||.|     :|
pombe   266 MSVLPGVTNYFLQLYINFSFTATGAGFTLIPTYQEVMASNCSKYDSTLMLTFIENHDLYRFPYYT 330

  Fly   388 ID-SRIITIAEDV---SGMPTLCRPVSEGGIGFDYRLGMAIPDKWIELLKEQSDDEWDMGNLVHT 448
            .| |:|:.....|   .|:|::.....:|..|.:.....  |..|:        .::|..|..:|
pombe   331 SDQSQIMGALSFVLIWDGIPSIFYGQEQGFNGGEDPANR--PALWL--------TDYDQSNPYYT 385

  Fly   449 LTNRR-------------WMENTVAYAESHDQALVGDKTIAFWLMDKEMYTHMSTLSDSSVIIDR 500
            :....             |:.:|....||.....||.|....     .|:.:|...::.::.
pombe   386 VIKTMVAFRKFVITQDPDWVTSTYQSIESAVDHYVGQKNDVL-----VMFNNMGVTNNLTIY--- 442

  Fly   501 GLALHKMIRLITHALGGEAYLNFMGNE-----FGH 530
                             |...|:..||     |||
pombe   443 -----------------EVETNYTANEVVSDVFGH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AGBE	NP_788342.1	GlgB	52..682	CDD:223373	87/425 (20%)
		E_set_GBE_euk_N	62..161	CDD:199884
		AmyAc_bac_euk_BE	167..570	CDD:200460	87/425 (20%)
		Alpha-amylase_C	588..683	CDD:280898
aah3	NP_587976.1	AmyAc_euk_AmyA	23..400	CDD:200458	71/338 (21%)
		Alpha-amylase	61..366	CDD:278554	66/294 (22%)
		DUF1966	<426..491	CDD:286359	9/60 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2134
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030