Protein Alignment CG33128 and PEP4

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_015171.1
• Gene: PEP4 / 855949
• SGDID: S000006075
• Length: 405
• Species: Saccharomyces cerevisiae
• Alignment Length: 421
• Identity: 158/421 - (37%)
• Similarity: 227/421 - (53%)
• Gaps: 42/421 - (9%)

  Fly     2 LKWLVLLTILAL----VSAEIHRIKIHKNQ---DHKNT--RQHRKQAIQALKLKYHQQDVVIIYD 57
            ||.|:.|.:|.:    |:|::|:.||:|::   :.|..  .||.....|....::.:.:..:::.
Yeast     4 LKALLPLALLLVSANQVAAKVHKAKIYKHELSDEMKEVTFEQHLAHLGQKYLTQFEKANPEVVFS 68

  Fly    58 DGVPIYMQPDYGYDYPSQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSA 122
            ...|.:.:.  |:|.|           |.|.:|..||..|.:|||.|.|||:.||||:||||||.
Yeast    69 REHPFFTEG--GHDVP-----------LTNYLNAQYYTDITLGTPPQNFKVILDTGSSNLWVPSN 120

  Fly   123 QCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAVS 187
            :|  ..:||..|::|:..|||::.::|..|:|||||||:.||::.||::|..|.|..|.|.||.|
Yeast   121 EC--GSLACFLHSKYDHEASSSYKANGTEFAIQYGTGSLEGYISQDTLSIGDLTIPKQDFAEATS 183

  Fly   188 QPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVD-GGQLTLG 251
            :||.:|....||||||:||..|:.|.|||||||..::.|:||..|.|||.......: ||:.|.|
Yeast   184 EPGLTFAFGKFDGILGLGYDTISVDKVVPPFYNAIQQDLLDEKRFAFYLGDTSKDTENGGEATFG 248

  Fly   252 GTDQNLIAGEMTYTPVTQQGYWQFAVNNITWN---GTVISSGCQAIADTGTSLIAAPSAAYIQLN 313
            |.|::...|::|:.||.::.||:.....|...   ..:.|.|  |..|||||||..||.....:|
Yeast   249 GIDESKFKGDITWLPVRRKAYWEVKFEGIGLGDEYAELESHG--AAIDTGTSLITLPSGLAEMIN 311

  Fly   314 NLIGGVP-IQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCMSTFT------ 371
            ..||... ..|.|.:.|:|..:||.|..|..|.||.:.|    ..||.....:|:|..|
Yeast   312 AEIGAKKGWTGQYTLDCNTRDNLPDLIFNFNGYNFTIGP----YDYTLEVSGSCISAITPMDFPE 372

  Fly   372 DIGTGFWILGDVFLGQYYSEFDFGQNRVGFA 402
            .:|. ..|:||.||.:|||.:|.|.|.||.|
Yeast   373 PVGP-LAIVGDAFLRKYYSIYDLGNNAVGLA 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	139/331 (42%)
PEP4	NP_015171.1	Proteinase_A_fungi	81..403	CDD:133155	140/342 (41%)