Protein Alignment CG33128 and YPS1

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_013221.1
• Gene: YPS1 / 850811
• SGDID: S000004110
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 486
• Identity: 106/486 - (21%)
• Similarity: 177/486 - (36%)
• Gaps: 145/486 - (29%)

  Fly    24 HKNQDHKNTRQHRKQAIQALKLKYHQQDVVIIYDDGVPIYMQPDYGYDYPSQTSV----DYTSEE 84
            :|..|..|::        .:||.:|:     :|.|.:     .:.|.|...:..:    |...|.
Yeast    28 NKRDDDSNSK--------FVKLPFHK-----LYGDSL-----ENVGSDKKPEVRLLKRADGYEEI 74

  Fly    85 LGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWV------------------------------ 119
            :..:...:|...:.:|||.|...|:.||||::||:
Yeast    75 IITNQQSFYSVDLEVGTPPQNVTVLVDTGSSDLWIMGSDNPYCSSNSMGSSRRRVIDKRDDSSSG 139

  Fly   120 ---------------------PSAQCL------ATD--------VACQQHNQYNSSASSTFVSSG 149
                                 |:|..|      ||.        :.|||:..:::|.||||.|:.
Yeast   140 GSLINDINPFGWLTGTGSAIGPTATGLGGGSGTATQSVPASEATMDCQQYGTFSTSGSSTFRSNN 204

  Fly   150 QNFSIQYGTGS-VSGYLAIDTVTINGLAIANQTFGEAVSQPGASFTDVAFDGILGMGYQQI---- 209
            ..|||.||.|: .||....|.:.::.|.:...:|..| ::..::.      |:||:|..::
Yeast   205 TYFSISYGDGTFASGTFGTDVLDLSDLNVTGLSFAVA-NETNSTM------GVLGIGLPELEVTY 262

  Fly   210 ------------AEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTLGGTDQNLIAGEM 262
                        ..||.  |.. |...|.|....:..||  |.|....|.:..|..|.:...|.:
Yeast   263 SGSTASHSGKAYKYDNF--PIV-LKNSGAIKSNTYSLYL--NDSDAMHGTILFGAVDHSKYTGTL 322

  Fly   263 TYTPV----TQQGY-----WQFAVNNI------TWNGTVISSGCQAIADTGTSLIAAPSAAYIQL 312
            ...|:    :..|:     :...:|.|      :.|.|:.::...|:.|:||:|...|......:
Yeast   323 YTIPIVNTLSASGFSSPIQFDVTINGIGISDSGSSNKTLTTTKIPALLDSGTTLTYLPQTVVSMI 387

  Fly   313 NNLIGGVPIQ--GDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCM----STFT 371
            ...:|.....  |.|.:.|.:..|:.:: .:.||.:...|.|.:|.:    ..|||:    .|..
Yeast   388 ATELGAQYSSRIGYYVLDCPSDDSMEIV-FDFGGFHINAPLSSFILS----TGTTCLLGIIPTSD 447

  Fly   372 DIGTGFWILGDVFLGQYYSEFDFGQNRVGFA 402
            |.||   ||||.||...|..:|.....:..|
Yeast   448 DTGT---ILGDSFLTNAYVVYDLENLEISMA 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	95/423 (22%)
YPS1	NP_013221.1	SAP_like	81..477	CDD:133141	94/415 (23%)