Protein Alignment CG33128 and Pga3

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_068521.1
• Gene: Pga3 / 60372
• RGDID: 621573
• Length: 387
• Species: Rattus norvegicus
• Alignment Length: 423
• Identity: 154/423 - (36%)
• Similarity: 226/423 - (53%)
• Gaps: 55/423 - (13%)

  Fly     2 LKWLVLLTILALVS--AEIHRIKIHKNQDHKNTRQHRKQAIQALKLKYHQQDVVIIYDDGVPIYM 64
            :|||.:|.::||..  .:|..:||      |:.|::.:::                       :|
  Rat     1 MKWLWVLGLVALSECLVKIPLMKI------KSMRENLRES-----------------------HM 36

  Fly    65 QPDYGYDYP---------SQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVP 120
            ..||...||         .:.:...|.|.:.|.:::.|.|.|.||||.|.||||.||||::||||
  Rat    37 LKDYLEKYPRSRAHVLLEQRRNPSVTYEPMRNYLDLVYIGTISIGTPPQEFKVVLDTGSSDLWVP 101

  Fly   121 SAQCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEA 185
            |..|  :..||..|..:|...||||:.||:..::.||:|.:||:||.|||.|..|.:..|.||.:
  Rat   102 SIYC--SSPACAHHKVFNPLQSSTFLVSGRPVNVAYGSGEMSGFLAYDTVKIGDLTVVAQAFGLS 164

  Fly   186 VSQPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTL 250
            :.:||.......||||||:||..:....|.|.|.||:.:|||.:.:|.|||:....  .|..|.|
  Rat   165 LEEPGRFMEHAVFDGILGLGYPNLGLQGVTPVFDNLWIQGLIPQNLFAFYLSSKDE--KGSVLML 227

  Fly   251 GGTDQNLIAGEMTYTPVTQQGYWQFAVNNITWNGTVIS--SGCQAIADTGTSLIAAPSAAYIQLN 313
            ||.|.:...||:.:.||::..|||.||::|:.||.:|:  .|||.|.||||||:..|.::.:.:.
  Rat   228 GGVDPSYYHGELHWVPVSKPSYWQLAVDSISMNGEIIACDGGCQGIMDTGTSLVTGPRSSILNIQ 292

  Fly   314 NLIGG-VPIQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCMSTF---TDIG 374
            ||||. ....|:|::.|.|:::||.:...|....:.:|.|.||:.....|   |.|.|   ||..
  Rat   293 NLIGAKASGDGEYFLKCDTINTLPDIVFTIDSVTYPVPASAYIRKDHSHN---CRSNFEESTDDP 354

  Fly   375 TG--FWILGDVFLGQYYSEFDFGQNRVGFATLA 405
            :.  .|:||||||..|::.||...||:|.|:.|
  Rat   355 SDPELWVLGDVFLRLYFTVFDRANNRIGLASAA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	135/327 (41%)
Pga3	NP_068521.1	A1_Propeptide	18..44	CDD:462326	8/54 (15%)
		pepsin_retropepsin_like	64..385	CDD:472175	135/327 (41%)