Protein Alignment CG33128 and REN

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_000528.1
• Gene: REN / 5972
• HGNCID: 9958
• Length: 406
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 127/351 - (36%)
• Similarity: 192/351 - (54%)
• Gaps: 14/351 - (3%)

  Fly    61 PIYMQPDYGYDYPSQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCL 125
            |.:.||.......:.||    |..|.|.|:..|||.||||||.|.|||||||||:|:||||::|.
Human    58 PEWSQPMKRLTLGNTTS----SVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCS 118

  Fly   126 ATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAVSQPG 190
            ....||..|..:::|.||::..:|...:::|.||:|||:|:.|.:|:.|:.: .|.|||....|.
Human   119 RLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITV-TQMFGEVTEMPA 182

  Fly   191 ASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARN--GSAVDGGQLTLGGT 253
            ..|....|||::|||:.:.|...|.|.|.|:..:|::.|.||.||..|:  .|...|||:.|||:
Human   183 LPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGS 247

  Fly   254 DQNLIAGEMTYTPVTQQGYWQFAVNNITWNGTVI--SSGCQAIADTGTSLIAAPSAAYIQLNNLI 316
            |.....|...|..:.:.|.||..:..::...:.:  ..||.|:.|||.|.|:..:::..:|...:
Human   248 DPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312

  Fly   317 GGVPIQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYI--QTYTEGNYTTCMSTFTDI--GTG- 376
            |......||.|.|:...:||.::.::||..:.|..:.|:  ::|:.....|......||  .||
Human   313 GAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGP 377

  Fly   377 FWILGDVFLGQYYSEFDFGQNRVGFA 402
            .|.||..|:.::|:|||...||:|||
Human   378 TWALGATFIRKFYTEFDRRNNRIGFA 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	121/329 (37%)
REN	NP_000528.1	A1_Propeptide	33..>51	CDD:462326
		renin_like	78..405	CDD:133154	121/327 (37%)