Protein Alignment CG33128 and Pga5

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_067428.2
• Gene: Pga5 / 58803
• MGIID: 1915935
• Length: 387
• Species: Mus musculus
• Alignment Length: 423
• Identity: 154/423 - (36%)
• Similarity: 225/423 - (53%)
• Gaps: 55/423 - (13%)

  Fly     2 LKWLVLLTILALVS--AEIHRIKIHKNQDHKNTRQHRKQAIQALKLKYHQQDVVIIYDDGVPIYM 64
            :|||.:|.::||..  .:|..:||      |:.|::.::: |.||
Mouse     1 MKWLWVLGLVALSECLVKIPLMKI------KSMRENLRES-QVLK-------------------- 38

  Fly    65 QPDYGYDYP---------SQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVP 120
              ||...||         .:.:...|.|.:.|.:::.|.|:|.||||.|.|:||.||||:.||||
Mouse    39 --DYLEKYPRSRAHVLLEQRRNPAVTYEPMRNYLDLVYIGIISIGTPPQEFRVVLDTGSSVLWVP 101

  Fly   121 SAQCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEA 185
            |..|  :..||..|..:|...||||:.||:..::.||:|.:||:||.|||.|..|.:..|.||.:
Mouse   102 SIYC--SSPACAHHKAFNPLRSSTFLVSGRPVNVAYGSGEMSGFLAYDTVRIGDLTVVAQAFGLS 164

  Fly   186 VSQPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTL 250
            :.:||.......||||||:||..:....:.|.|.||:.:|||.:.:|.|||:....  .|..|.|
Mouse   165 LEEPGIFMEYAVFDGILGLGYPNLGLQGITPVFDNLWLQGLIPQNLFAFYLSSKDE--KGSMLML 227

  Fly   251 GGTDQNLIAGEMTYTPVTQQGYWQFAVNNITWNGTVIS--SGCQAIADTGTSLIAAPSAAYIQLN 313
            ||.|.:...||:.:.||::..|||.||::|:.||.||:  .|||.|.||||||:..|.::.:.:.
Mouse   228 GGVDPSYYHGELHWVPVSKPSYWQLAVDSISMNGEVIACDGGCQGIMDTGTSLLTGPRSSIVNIQ 292

  Fly   314 NLIGG-VPIQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCMSTFTD----- 372
            ||||. ....|:|::.|.|:::||.:...||...:.:|.|.||:.....|   |.|.|.:
Mouse   293 NLIGAKASGDGEYFLKCDTINTLPDIVFTIGSVTYPVPASAYIRKDRSHN---CRSNFEEGMDDP 354

  Fly   373 IGTGFWILGDVFLGQYYSEFDFGQNRVGFATLA 405
            .....|:||||||..|::.||...||:|.|..|
Mouse   355 SDPEMWVLGDVFLRLYFTVFDRANNRIGLAPAA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	133/327 (41%)
Pga5	NP_067428.2	A1_Propeptide	18..44	CDD:462326	10/54 (19%)
		pepsin_retropepsin_like	64..385	CDD:472175	133/327 (41%)