DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33128 and cathD

DIOPT Version :9

Sequence 1:	NP_787961.1	Gene:	CG33128 / 326263	FlyBaseID:	FBgn0053128	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001334713.1	Gene:	cathD / 45268	FlyBaseID:	FBgn0029093	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	181/418 - (43%)
Similarity:	240/418 - (57%)	Gaps:	52/418 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVLLTILALVSAEIH----------RIKIHKNQDHKNTRQHRKQA---IQALKLKYHQQDVVIIY 56
            :.||.:..|.:|..|          |:.:||.|   :.|:|....   :|.|:::|.
  Fly     4 VALLLVAFLAAAVAHPNSQEKPGLLRVPLHKFQ---SARRHFADVGTELQQLRIRYG-------- 57

  Fly    57 DDGVPIYMQPDYGYDYPSQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPS 121
                        |.|.|         |.|.|.|:..|||.|.||:|.|.|:|||||||:||||||
  Fly    58 ------------GGDVP---------EPLSNYMDAQYYGPIAIGSPPQNFRVVFDTGSSNLWVPS 101

  Fly   122 AQCLATDVACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAV 186
            .:|..|::||..||:|::|.|.|:..:|..|:||||:||:||||:.|||:|.||.|.:|||.||:
  Fly   102 KKCHLTNIACLMHNKYDASKSKTYTKNGTEFAIQYGSGSLSGYLSTDTVSIAGLDIKDQTFAEAL 166

  Fly   187 SQPGASFTDVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTLG 251
            |:||..|....||||||:||..|:.|.|.||||.:||:|||..|||.|||.|:.::.:||::..|
  Fly   167 SEPGLVFVAAKFDGILGLGYNSISVDKVKPPFYAMYEQGLISAPVFSFYLNRDPASPEGGEIIFG 231

  Fly   252 GTDQNLIAGEMTYTPVTQQGYWQFAVNNITWNG-TVISSGCQAIADTGTSLIAAPSAAYIQLNNL 315
            |:|.|...||.||.|||::.|||..::..:... .:...|||.||||||||||||......:|..
  Fly   232 GSDPNHYTGEFTYLPVTRKAYWQIKMDAASIGDLQLCKGGCQVIADTGTSLIAAPLEEATSINQK 296

  Fly   316 IGGVP-IQGDYYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCMSTFTDI-----G 374
            |||.| |.|.|.|.|..:..|||:...:||..|.|....||....:...|.|:|.|..:     .
  Fly   297 IGGTPIIGGQYVVSCDLIPQLPVIKFVLGGKTFELEGKDYILRVAQMGKTICLSGFMGLDIPPPN 361

  Fly   375 TGFWILGDVFLGQYYSEFDFGQNRVGFA 402
            ...|||||||:|:||:|||.|.:|||||
  Fly   362 GPLWILGDVFIGKYYTEFDMGNDRVGFA 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:299705	164/327 (50%)
CG33128	NP_787961.1	Asp	92..404	CDD:278455	160/318 (50%)
cathD	NP_001334713.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455563
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900