Protein Alignment CG33128 and bace2

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_009289748.1
• Gene: bace2 / 449818
• ZFINID: ZDB-GENE-041010-68
• Length: 503
• Species: Danio rerio
• Alignment Length: 368
• Identity: 98/368 - (26%)
• Similarity: 158/368 - (42%)
• Gaps: 58/368 - (15%)

  Fly    78 VDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQH----NQYN 138
            :|..:...|:|...||..:| ||||.|...::.||||:|.          .||...|    :.:|
Zfish    66 LDMINNLKGDSGRGYYMQMI-IGTPGQTLNILVDTGSSNF----------AVAAAAHPYITHYFN 119

  Fly   139 SSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTI----NGLAIANQTFGEAVSQPGASFTDVAFD 199
            .:.|||:.|:.:..:::|..|...|.|..|.:||    :|....|  ....::..|.....:.:.
Zfish   120 RALSSTYQSTERAVAVKYTQGEWEGELGTDLITIPEGPSGAITIN--IAAILTSEGFFLPGINWQ 182

  Fly   200 GILGMGYQQIAE-DNVVPPFYN--LYEEGLIDEPVFGFYLARNGSAVD------GGQLTLGGTDQ 255
            ||||:.|..:|. |..|.||:|  :.:.|:.|  ||...:...|....      ||.|.:||.:.
Zfish   183 GILGLAYPLLARPDPSVEPFFNSVVRQTGIPD--VFSLQMCGAGVPASTTGDPAGGSLIMGGVEP 245

  Fly   256 NLIAGEMTYTPVTQQGYWQFAVNNITWNGTVISSGC------QAIADTGTSLIAAPSAAYIQLNN 314
            .|..|.:.||||.::.|:|..|..:......::..|      :||.|:||:|:..|:..:..:.:
Zfish   246 TLHRGPIWYTPVLEEWYYQVEVLKLEVGDQNLNLDCKEYNSDKAIVDSGTTLLRLPANVFTAVVD 310

  Fly   315 LIGGVPIQGDY--------YVPC-----STVSSLPVLTINIGGTN------FYLPPSVYIQTYTE 360
            .|....:..|:        .:.|     |.....|.::|.:.|||      ..:.|.:|||..|:
Zfish   311 TIMQTSLIDDFSAGFFDGTKLACWMRGESPWRFFPKVSIYLRGTNTSQSFRITILPQLYIQPVTD 375

  Fly   361 GNYT-TCMSTFTDIGTGFWILGDVFLGQYYSEFDFGQNRVGFA 402
            .:.| .|............::|...:..:|..||..|.|||||
Zfish   376 IDGTLDCFRFGISPSANGLVIGATVMEGFYVIFDRAQKRVGFA 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	97/363 (27%)
bace2	XP_009289748.1	beta_secretase_like	77..439	CDD:133140	95/357 (27%)