Protein Alignment CG33128 and bace1

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_001428889.1
• Gene: bace1 / 403005
• ZFINID: ZDB-GENE-040426-1835
• Length: 522
• Species: Danio rerio
• Alignment Length: 376
• Identity: 87/376 - (23%)
• Similarity: 152/376 - (40%)
• Gaps: 82/376 - (21%)

  Fly    93 YYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQ--HNQYNSSASSTFVSSGQNFSIQ 155
            ||..:.:|:|.|...::.||||:|        .|...|...  |..|:.|.||::...|:...:.
Zfish    80 YYIEMAVGSPAQRLNILVDTGSSN--------FAVGAAAHPFLHRYYHRSLSSSYRDLGRGVYVP 136

  Fly   156 YGTGSVSGYLAIDTVTIN-GLAIANQTFGEAVSQPGASFTDVA-FDGILGMGYQQIAE-DNVVPP 217
            |..|...|.|..|.|::. |..::.:....|::|....|.:.: ::||||:.|.:||. |..:.|
Zfish   137 YTQGRWEGELGTDVVSVPCGPNVSLRANIAAITQSDRFFINGSNWEGILGLAYAEIARPDETLEP 201

  Fly   218 FY-NLYEEGLIDEPVFGFYLARNG---------SAVDGGQLTLGGTDQNLIAGEMTYTPVTQQGY 272
            |: :|..:..:.: ||...|...|         |:..||.:.:||.|.:|..||:.|||:.::.|
Zfish   202 FFDSLLRQSTVAD-VFSLQLCGAGYSHNYSTGSSSTVGGSMIIGGVDPSLYVGELWYTPIRREWY 265

  Fly   273 WQFAVNNITWNGTVISSGC------QAIADTGTSLIAAPSAAYIQLNNLIGGVPIQGDYYVPCST 331
            ::..:..|..||..::..|      ::|.|:||:.:..|...:   ...:..:......|...|.
Zfish   266 YEVIIVRIEVNGQDLNMDCKEYNYDKSIVDSGTTNLRLPRKVF---QAAVKAIEAASSVYSEYSC 327

  Fly   332 VSS---------------------------------LPVLTINIGGTN------------FYLPP 351
            ..|                                 .||:::.:...|            .||.|
Zfish   328 AHSDSAWCPQTEQFPSGFWLGEQLVCWQAGTTPWHIFPVISLYLMSENRNQSFRISILPQQYLRP 392

  Fly   352 SVYIQTYTEGNYTTCMSTFTDIGTGFWILGDVFLGQYYSEFDFGQNRVGFA 402
            ...:.:..|..|...:|. :..||   ::|.|.:..:|..|:....|:|||
Zfish   393 VEDVASAQEDCYKFAVSQ-SSTGT---VMGAVIMEGFYVVFERQHKRIGFA 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	87/376 (23%)
bace1	NP_001428889.1	None