Protein Alignment CG33128 and Bace

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_609235.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 210/406 - (51%)
• Similarity: 274/406 - (67%)
• Gaps: 35/406 - (8%)

  Fly     1 MLKWLVLLTIL-ALVSAEIHRIKIHKNQDHKNTRQHRKQAIQALKLKYHQQDVVIIYDDGVPIYM 64
            |.|.:.::.:| ||.|||:||:.|.|.|:...|||:.......|:.|
  Fly     1 MFKTIAVVVLLAALASAELHRVPILKEQNFVKTRQNVLAEKSYLRTK------------------ 47

  Fly    65 QPDYGYDYPSQTSVDYTSEELGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDV 129
                 |..||..|||  .|:|.|||||.|||.|.||||.|.|||:||:||:||||||..|.:.
  Fly    48 -----YQLPSLRSVD--EEQLSNSMNMAYYGAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSD-- 103

  Fly   130 ACQQHNQYNSSASSTFVSSGQNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAVSQPGASFT 194
            ||..||||:||||||:|::|::|||||||||::|||:.|||.:|||:|.:|||.|:.::||.:|.
  Fly   104 ACLTHNQYDSSASSTYVANGESFSIQYGTGSLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFN 168

  Fly   195 DVAFDGILGMGYQQIAEDNVVPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTLGGTDQNLIA 259
            |..|||||||.|:.:|.|.|.|||||:..:||:|..||.|||||:|::..||:|..||:|.:|.:
  Fly   169 DANFDGILGMAYESLAVDGVAPPFYNMVSQGLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYS 233

  Fly   260 GEMTYTPVTQQGYWQFAVNNITWNGTVISSGCQAIADTGTSLIAAPSAAYIQLNNLIGGVPIQGD 324
            |.:||.|:::||||||.:...:.:|..:...||||||||||||.||..|||.|:.::.   :..|
  Fly   234 GALTYVPISEQGYWQFTMAGSSIDGYSLCDDCQAIADTGTSLIVAPYNAYITLSEILN---VGED 295

  Fly   325 YYVPCSTVSSLPVLTINIGGTNFYLPPSVYIQTYTEGNYTTCMSTFTDIGTGFWILGDVFLGQYY 389
            .|:.||:|||||.:|.|||||||.|.||.|| ..::||   |||.|..:||.||||||||:||||
  Fly   296 GYLDCSSVSSLPDVTFNIGGTNFVLKPSAYI-IQSDGN---CMSAFEYMGTDFWILGDVFIGQYY 356

  Fly   390 SEFDFGQNRVGFATLA 405
            :|||.|.||:|||.:|
  Fly   357 TEFDLGNNRIGFAPVA 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	184/319 (58%)
Bace	NP_609235.1	pepsin_retropepsin_like	59..369	CDD:472175	183/318 (58%)