Protein Alignment CG33128 and Ren2

DIOPT Version :10

• Sequence 1: NP_787961.1
• Gene: CG33128 / 326263
• FlyBaseID: FBgn0053128
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: NP_112470.2
• Gene: Ren2 / 19702
• MGIID: 97899
• Length: 424
• Species: Mus musculus
• Alignment Length: 326
• Identity: 126/326 - (38%)
• Similarity: 188/326 - (57%)
• Gaps: 10/326 - (3%)

  Fly    85 LGNSMNMYYYGLIGIGTPEQYFKVVFDTGSANLWVPSAQCLATDVACQQHNQYNSSASSTFVSSG 149
            |.|.:|..|||.||||||.|.|||:||||||||||||.:|....:||..|:.|.||.||:::.:|
Mouse    98 LTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHSLYESSDSSSYMENG 162

  Fly   150 QNFSIQYGTGSVSGYLAIDTVTINGLAIANQTFGEAVSQPGASFTDVAFDGILGMGYQQIAEDNV 214
            .:|:|.||:|.|.|:|:.|:||:.|:.: .|||||....|...|....|||:||||:...|...|
Mouse   163 DDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAQFDGVLGMGFPAQAVGGV 226

  Fly   215 VPPFYNLYEEGLIDEPVFGFYLARNGSAVDGGQLTLGGTDQNLIAGEMTYTPVTQQGYWQFAVNN 279
            .|.|.::..:|::.|.||..|..| |..:.||::.|||:|.....|:..|..:::...||..:..
Mouse   227 TPVFDHILSQGVLKEKVFSVYYNR-GPHLLGGEVVLGGSDPEHYQGDFHYVSLSKTDSWQITMKG 290

  Fly   280 ITWNGTVI--SSGCQAIADTGTSLIAAPSAAYIQLNNLIGGVPIQ-GDYYVPCSTVSSLPVLTIN 341
            ::...:.:  ..||:.:.|||:|.|:||:::...:...:|....: .:|.|.||.|.:||.::.|
Mouse   291 VSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVSCSQVPTLPDISFN 355

  Fly   342 IGGTNFYLPPSVYIQTYTEGNYTTCMSTF--TDI--GTG-FWILGDVFLGQYYSEFDFGQNRVGF 401
            :||..:.|..:.|:..|.......|....  .||  .|| .|:||..|:.::|:|||...||:||
Mouse   356 LGGRAYTLSSTDYVLQYPNRRDKLCTVALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGF 420

  Fly   402 A 402
            |
Mouse   421 A 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33128	NP_787961.1	pepsin_retropepsin_like	83..403	CDD:472175	126/326 (39%)
Ren2	NP_112470.2	A1_Propeptide	53..>71	CDD:462326
		renin_like	98..423	CDD:133154	126/326 (39%)