Protein Alignment LeuRS and LeuRS-m

DIOPT Version :10

• Sequence 1: NP_787968.1
• Gene: LeuRS / 326262
• FlyBaseID: FBgn0284253
• Length: 1182
• Species: Drosophila melanogaster
• Sequence 2: NP_647932.1
• Gene: LeuRS-m / 38581
• FlyBaseID: FBgn0027085
• Length: 869
• Species: Drosophila melanogaster
• Alignment Length: 1038
• Identity: 178/1038 - (17%)
• Similarity: 296/1038 - (28%)
• Gaps: 439/1038 - (42%)

  Fly    13 EYLQKIEREVQQRWEAERVHESDAPTAPKKRQAEKFFVTFPFPYMNGRLHLGHTFSLSKAEYSMR 77
            |....::..::..|   |...|.....||..| :|::|...|||.:|.||:||....:.|:...|
  Fly    33 ELTSDVKHRIEAHW---REQLSGGQFNPKDSQ-DKYYVLSMFPYPSGNLHMGHVRVYTIADSVAR 93

  Fly    78 YHRLKGRRVLWPFGFHCTGMPIKACADKLTRELEQFGFPPQFPETEEVVPVAAEAASEVPKDKSK 142
            :.|:.|:.|..|.|:                  :.||.|            |..||::
  Fly    94 FQRMCGKNVFQPMGW------------------DSFGLP------------AENAANQ------- 121

  Fly   143 GKKSKAVAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRRTFI 207
                     .|.....|.......:|::                      |||:|...||.....
  Fly   122 ---------RGVEPASWTEQNIAQMKEQ----------------------LKRLGCSFDWNHELS 155

  Fly   208 TTDANPYFDSFVRWQFNHLKERGKIMYGKRYTIYSPKDGQPCMDHDRSSGEGVGPQEYTLIKMKV 272
            |  .:|.:..:.:..|..|...|.....:....:.|.|.....|.
  Fly   156 T--CSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADE-------------------- 198

  Fly   273 LEVPKALSSIKQPIFMVAATLRPETMYGQTNCWLHPDIKYIAWQANKNNEVWVSTRRAARNMTYQ 337
                                                       |.:.|...|.|..:..:.:..|
  Fly   199 -------------------------------------------QVDANGCSWRSGAKVEKKLLRQ 220

  Fly   338 GFTAVEGEIKVLAEVTG---------QDLLGVPLSAPLTKHKV----VYSLPMLSIKEDKGTGVV 389
            .|.......|.|.:  |         :|::.      |.:|.:    .|:..:|:    ..:|::
  Fly   221 WFIRTSAYAKQLLD--GLEDPTLRDWRDIIN------LQRHWIGECDGYAFNLLT----SASGLL 273

  Fly   390 ---TSVPSDSPDDYAALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKI 451
               |:.|....|.:|.||                                              :
  Fly   274 RVWTTHPEHLKDPHAFLV----------------------------------------------L 292

  Fly   452 QSQNDKDKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDLQKRLVDANEADVYYEPEKTI-- 514
            :|.:...||..|          |.:.....|||..:..|..|           :|.:.|:..:
  Fly   293 RSNHHLSKLKGA----------DSLSAANPFAGTTMPVVFSD-----------EVTFPPKSDVYL 336

  Fly   515 ---MSRSADECVVALCNQW------YLNYGEPE-------WQAQATKILHGMETFHEEARNNFEA 563
               ..|..|:      :.|      :.:.|:.|       |:....::|......:.........
  Fly   337 AAPSFRGEDK------DLWDSYGLAFTSNGKDEESLSPANWEMLRKEVLQAATRLNVGGYRVSSK 395

  Fly   564 CLNWLHEYACSRTYGLGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFR-GEKPGPFGIKP 627
            ..:||    .||....||.:|                     :||..:.|... .|:..|..:.|
  Fly   396 LKDWL----ISRQRYWGTPIP---------------------IVHCQKCGAVPVPEEQLPVSLPP 435

  Fly   628 SDMTGEI---------------------------WDYIFFK---------ETPLPKKTAIKQEHL 656
            .|...|.                           |.|:.:.         :|.|.||
  Fly   436 KDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKK-------- 492

  Fly   657 AVLRREFEYWYPMDLRVSGKDLIQNHLTFCLY-NH----AAIWPNDENKWP------KGM----- 705
                     :.|:||.:.||:....||.:..: ||    ..:.|..|   |      :||
  Fly   493 ---------FMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSE---PFSRLLVQGMVMGRS 545

  Fly   706 -RVNGH---------------------------LLLNSAKMSKSDGNFLTLTEAVDKFSADGMRL 742
             ||.|.                           :::...|||||..|.:..::..:::..|..||
  Fly   546 FRVKGSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRL 610

  Fly   743 -CLADAGDSVEDANFVESTADAGILRLYTFIEWVKEM---LENRSSLRKGTDKTFNDQV-----F 798
             .|||...: ...|:..:|. .|||      .|.|.:   |::....|:  |:|.:|.|     |
  Fly   611 IILADVAPT-SHRNWSSATF-PGIL------NWQKRLWLTLQDFQQARE--DQTASDVVPTSEEF 665

  Fly   799 LSE-------LNLKTQQTDENYRKMLFKEALRSGFYELQLARDKYRELCGANGMHEDLVL----E 852
            |:|       .|...:....|||..          .:|.:|..|.:.|..:.......||    :
  Fly   666 LAEDAKLFDARNFYVKGATFNYRHA----------QQLSVAISKMQGLTNSLRRTPKHVLRHGKQ 720

  Fly   853 FIR---RQALLVSPICPHMAEHVW-------GLLGN-------KESIVHARWPEVGAINEVDI 898
            |.|   .|.::::|:.||.|..:|       |.|..       .|.::..|||::.....:|:
  Fly   721 FERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDL 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LeuRS	NP_787968.1	PLN02959	1..1068	CDD:215518	178/1038 (17%)
LeuRS-m	NP_647932.1	LeuS	40..848	CDD:440261	177/1031 (17%)