Protein Alignment Spn28Db and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 102/424 - (24%)
• Similarity: 182/424 - (42%)
• Gaps: 88/424 - (20%)

  Fly    22 KFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDL-------------- 71
            ||..:|. |:..|....|...|||.:...:.|:.:||:..:|.::..||..
Human    22 KFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPC 86

  Fly    72 ----------------------PVD----------------VTEMAKKYERIMSNFQKHNGLRFT 98
                                  |:|                ..::..|.:||.:::.    |...
Human    87 LKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYT----LSIA 147

  Fly    99 NWLYVNETYEVRQD--------YNTLMKSTFMAEGKDPLSQRKASNSISFSIHRKSHKGMRTISN 155
            |.||..:.:.:.|:        |:|.::|....  |:|   .|:...|:|.:..:|...::.:.:
Human   148 NRLYGEQEFPICQEYLDGVIQFYHTTIESVDFQ--KNP---EKSRQEINFWVECQSQGKIKELFS 207

  Fly   156 DHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVGRFRIA--DHSYG 218
            ...:......||||.||:...|:|.|..::|....|..:.|:...|:||:..|.:||.  :....
Human   208 KDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 272

  Fly   219 QIIEMPFDNSDLSMIIGLPLHN-TYLSSIEKILRTL----------SESLVENNVHVELPKFKIK 272
            ||:||.:....|||.:.||.|: ..|..:|::.|.:          ||::.|.:|.:..|:|.::
Human   273 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLE 337

  Fly   273 YQTELVESLKKLGIHLIFSNT-SDLSGLLTNGTGAKINHVVHKSFIEINERGASTGEASDHAESI 336
            ...:|...|:.:||..||..| :||:| ::......::.::||:|:|::|.|.....|:....|
Human   338 DSYDLNSILQDMGITDIFDETRADLTG-ISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVS- 400

  Fly   337 QKKTRASTSFKVNRPFVFLIRDK--HTVYFRGRV 368
            ::..|:...|..|.||:|.||..  .|:.|.|||
Human   401 ERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRV 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	100/422 (24%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	102/424 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.930