Protein Alignment Spn28Db and SERPINB7

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001035237.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 96/388 - (24%)
• Similarity: 174/388 - (44%)
• Gaps: 61/388 - (15%)

  Fly    22 KFKLNLL-ELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPV---------DVT 76
            :|..||. |:..::...|...|.|.:...::::.:||:..:..::..:|.:..         ..:
Human    10 EFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASGYGNSSNSQS 74

  Fly    77 EMAKKYERIMSNF---QKHNGLRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDPLSQRKASNSI 138
            .:..:.:|:.|:.   .|...|...|.|:..:.|...:||         .|..:.|...|... :
Human    75 GLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDY---------IECAEKLYDAKVER-V 129

  Fly   139 SFSIH-------------RKSHKGMRTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTKLKV 190
            .|:.|             .::|..::.:..:..:..:...||||.||:.|.|::.|:|.:|....
Human   130 DFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCH 194

  Fly   191 FHGDHNKKVYVRMMSHVGRFR---IADHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIEKILR- 251
            |.........|.||....:|.   |.|.|. :|:|:.: |..::|.:.||.::  ||.||..|.
Human   195 FKSPKCSGKAVAMMHQERKFNLSVIEDPSM-KILELRY-NGGINMYVLLPEND--LSEIENKLTF 255

  Fly   252 ------TLSESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNT-SDLSGLLTNGTGAKIN 309
                  |....:....|.|..|:|||:...|:.:.|:.||:..||..: :||||:.:.|. ..|:
Human   256 QNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGR-LYIS 319

  Fly   310 HVVHKSFIEINERG----ASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRDKHTVYFRGRV 368
            .::|||:||:.|.|    |:||     :..::|:...||.|:.:.||:|:||....:.|.|:|
Human   320 RMMHKSYIEVTEEGTEATAATG-----SNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSGKV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	95/386 (25%)
SERPINB7	NP_001035237.1	serpinB7_megsin	1..380	CDD:381032	96/388 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930