DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and Serpine3

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_006252257.2	Gene:	Serpine3 / 691375	RGDID:	1585042	Length:	413	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	96/418 - (22%)
Similarity:	171/418 - (40%)	Gaps:	98/418 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLIATSVLGKFKLNLLELVMDKAE-SNFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVD- 74
            |.|:.|    :|.|:|.:....:.. :||:.||..:.:.:.::...|:|.|..:|...|...|.
  Rat    28 LWLLKT----EFALHLYQSAAAETNGTNFVISPASVSLSLEILQFAARGNTGWQLAEALGYTVQD 88

  Fly    75 --VTEMAKKYERIMSNFQKHNGLRFTNWLYV------------------NETYEVRQDYNTLMKS 119
              |.|........:.|..:..|:.....|::                  |.:.|: .|::....:
  Rat    89 PRVREFLHTVYITLHNSSQGIGMELACTLFMQTGTSLSPCFVEQVSRWANSSLEL-ADFSEPNTT 152

  Fly   120 TFMA----------EGK-DPLSQRKASNSISFSIHRKSHKGMRTISNDHNLQINESAVLVNTVYY 173
            |..|          ||. .||..|..:.|...||                         |:|:.:
  Rat   153 TMEASKGTTRPSTGEGPGSPLWGRAGALSTQLSI-------------------------VSTMTF 192

  Fly   174 SGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVGRFRIADHSYGQ----------IIEMPFDNS 228
            ..:|:.|||....:...|...|...:.|..|     .::|:.||||          ::|:.:...
  Rat   193 QSSWQQRFSSVALQPLPFTCAHGLVLQVPAM-----HQVAEVSYGQFQDAAGHKVDVLELLYLGR 252

  Fly   229 DLSMIIGLPL-HNTYLSSIE-----KILRTLSESLVENNVHVELPKFKIKYQTELVESLKKLGIH 287
            ..|:::.||. ..|.|..||     :::...:..|....:.|.||:|:|:.|.:|...|:..||.
  Rat   253 VASLLLVLPQDKGTPLDHIEPHLTARVIHLWTTRLKRARMDVFLPRFRIQNQFDLKSILRSWGIT 317

  Fly   288 LIF----SNTSDLSGLLTNGTGAKINHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKV 348
            .:|    :|...:||    ..|..::.|.||:.:|::|.|..:..|:  |..:.:::| :.:||.
  Rat   318 DLFDPLKANLKGISG----RDGFYVSEVTHKAKMELSEEGTKSCAAT--AVLLLRRSR-TPAFKA 375

  Fly   349 NRPFVFLIRDKHTVYFR---GRVVRLPN 373
            :|||:||:|:.:||..|   |:|....|
  Rat   376 DRPFIFLLREHNTVAVRITHGKVANFLN 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	91/401 (23%)
Serpine3	XP_006252257.2	serpin	20..400	CDD:422956	95/413 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110