Protein Alignment Spn28Db and SERPINE3

DIOPT Version :10

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 58/303 - (19%)
• Similarity: 98/303 - (32%)
• Gaps: 91/303 - (30%)

  Fly   117 PLLFLWRSLQAQLPWESCGNAWNTPRCLELRGDQH---------------VELFLNNSAMAIGDR 166
            |||...:||:..|..|:........:...||..|.               |||...:..:..||.
Human    50 PLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVVDPKDVTLDLVELTFKDQYIGRGDM 114

  Fly   167 YLLEVVESLLEHQGLFLVVVCSNEILHISE-----GIEQMGGIVW---PLLLCDVIA--WIVIFG 221
            :.|:          ..||..|:    :|::     ||....|.:|   ..::|..|:  ..|:|
Human   115 WRLK----------KSLVSTCA----YITQKVEFAGIRAQAGELWVKNEKVMCGYISEETRVVF- 164

  Fly   222 CIAKGVQSVGKVVYCTATFPFAILAVLLVRGITLPGALEGIKFYIMPQWSQ---------LLNLR 277
                  :|...:||........:....:...:....|:.|....:..:|.:         :|..|
Human   165 ------RSTSAMVYIFIQMSCEMWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSR 223

  Fly   278 VWADA-AIQIFYSLGPGWGGILNMAS---------YNQF-------KNNTKLDSIVIPIVNCGTS 325
            .:.|| :|..|..        :|.||         |..|       :...:..|:::.|...
Human   224 TFYDAKSIDEFPE--------INRASIQEDHKGRFYEDFYKVVVQNERREEWTSLLVTIKKL--- 277

  Fly   326 ILAGFVVFSVLGYFSHQTGLPVASAATGGPGLAFITYPEAISM 368
                |:.:.||.......|.|....:|...|    .|.|||::
Human   278 ----FIQYPVLVRLEQAGGFPQGDNSTSAQG----NYLEAINL 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	serpin	18..370	CDD:476815	58/303 (19%)
SERPINE3	NP_001094790.1	serpinE3	18..400	CDD:381040	58/303 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		8/37 (22%)