Protein Alignment Spn28Db and SERPINB4

DIOPT Version :9

• Sequence 1: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 116/388 - (29%)
• Similarity: 189/388 - (48%)
• Gaps: 53/388 - (13%)

  Fly    22 KFKLNLLELVMDKAESNFIASPLCIEIGISMILMGAKGTTAEELRSVL---DLPVDVTEMAKKY- 82
            ||..:|.:......|:|...||:.|...:.|:|:|||..||:::..||   .:..:.||.|..|
Human    10 KFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYH 74

  Fly    83 -----------ERIMSNFQKHNG---LRFTNWLYVNETYEVRQD--------YNTLMKSTFMAEG 125
                       :::::.|.|...   |:..|.|:..:||:..|:        |.|.::||..|..
Human    75 VDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANA 139

  Fly   126 KDPLSQRKASNSISFSIHRKSHKGM---RTISNDHNLQINESAVLVNTVYYSGAWKTRFSKKDTK 187
              |...||..||...|...:..|.:   .||.||..|      ||||.:|:.|.|:.:|.|::||
Human   140 --PEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTL------VLVNAIYFKGQWENKFKKENTK 196

  Fly   188 LKVFHGDHNKKVYVRMMSHVGRFRIA--DHSYGQIIEMPFDNSDLSMIIGLPLHNTYLSSIEKIL 250
            .:.|..:.|....|:||.....|..|  :....:::|:|:...|||||:.||.....|..:|:.|
Human   197 EEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKL 261

  Fly   251 R-------TLSESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLSGLLTNGTGAKI 308
            .       |..:::.|..|.:.||:||::...:|.::|:.:|:..||:..:|||| :|...|..:
Human   262 TAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSG-MTWSHGLSV 325

  Fly   309 NHVVHKSFIEINERGASTGEASDHAESIQKKTRASTS--FKVNRPFVFLIRDKHT--VYFRGR 367
            :.|:||:|:|:.|.|.....|:  |..:.:.:..||:  |..|.||:|.||...|  :.|.||
Human   326 SKVLHKAFVEVTEEGVEAAAAT--AVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYGR 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	116/388 (30%)
SERPINB4	NP_002965.1	SERPIN	4..390	CDD:320777	116/388 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H76659
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830