DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Db and serpinf2a

DIOPT Version :9

Sequence 1:	NP_001356884.1	Gene:	Spn28Db / 326261	FlyBaseID:	FBgn0053121	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	XP_688797.1	Gene:	serpinf2a / 560308	ZFINID:	ZDB-GENE-060822-1	Length:	457	Species:	Danio rerio

Alignment Length:	386	Identity:	104/386 - (26%)
Similarity:	179/386 - (46%)	Gaps:	68/386 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SVLGKFKLNLLELVMDKAES-NFIASPLCIEIGISMILMGAKGTTAEELRSVL---DLPVDVTEM 78
            :.:.|..|.|||.:...:|. |.|.|||.:.:.::.:.:||:..|.|:|..||   :||
Zfish    45 AAVAKLGLTLLEKLQPGSEQPNIIISPLSVSLALAELALGARNNTEEKLLEVLHAKELP------ 103

  Fly    79 AKKYERIMSNFQKH---NGLRFTNWLYVNETYEVRQDYNTLMKSTFMAEGKDPLSQRKASNSISF 140
              .:...:|..|:|   ..::..:.||:...|.|..|:.....:.:.:|.    :|..:...::
Zfish   104 --HFHETLSCLQEHLTAKAVKMASRLYLVPGYTVNPDFVDRALNLYKSES----AQLTSIEDVN- 161

  Fly   141 SIHRKSHKGMRTISNDHNLQI---------NESAVLVNTVYYSGAWKTRFSKKDTKLKVFHGDHN 196
                      |.:....|.||         |...:|:|.:::.|.|::||:.|.||..:||.|..
Zfish   162 ----------RWVEETTNGQITNFMSSLPPNVVLMLINAIHFKGEWQSRFNSKYTKENIFHIDRK 216

  Fly   197 KKVYVRMM--SHVGRFRIADHSYG-QIIEMPFDNSDLSMIIGLP-LHNTYLSSIEKILRTLSESL 257
            ..|.|.||  |........|.:.| |:..:|| ..::|:::.:| |.:..||::...| .:|:..
Zfish   217 TSVKVDMMMGSQYPLSMFVDRTDGTQVARLPF-RGNMSLLVIMPRLQHENLSNVAAKL-NISDMY 279

  Fly   258 V----ENNVHVELPKFKIKYQTELVESLKKLGIHLIFSNTSDLS----GLLTNGTGAKINHVVHK 314
            .    |.::||.|||||::|:.:|.::|..:|:..:|:. .|||    |.|.      ::.|.|.
Zfish   280 ARFPRERSMHVTLPKFKLEYKQDLRQALTSMGLGFLFTG-PDLSRIAPGPLV------VSGVQHA 337

  Fly   315 SFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRD--KHTVYFRGRVVRLPN 373
            |.:|::|.||....|:...     ..|..:.|.||.||:|.:.|  .:|..|.| :|..||
Zfish   338 SNMELSEEGAEASAATSFT-----LVRTISFFSVNMPFIFALVDDTSYTPLFLG-IVTNPN 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	101/375 (27%)
serpinf2a	XP_688797.1	SERPIN	54..388	CDD:294093	99/371 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.100